(Z)-2-(4-((5-((1-苄基胡椒-4-基)亚甲基)-2,4-二氧噻唑烷-3-基)甲基)- 1h -1,2,3-三唑-1-基)- n-苯乙酰胺的合成及抑菌活性

Ashok Rathod, Kapilkumar Galachar, C. Pashavan, S. Korgaokar, Y. Naliapara
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引用次数: 0

摘要

目前,研究人员采用点击化学方法,通过点击形成过程中几种可靠、可行、实用、选择性强的化学转化,来合成各种类药物分子。在目前的工作中,我们重点研究了三唑棒状噻唑烷-2,4-二酮衍生物作为最有希望广泛应用的基序。共合成了15个(CF-4a-o)衍生物,并用各种分析技术对其进行了表征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Synthesis and Antimicrobial Activity of (Z)-2-(4-((5-((1-Benzylpiperidin-4-yl)methylene)- 2,4-dioxothiazolidin-3-yl)methyl)-1H-1,2,3-triazol-1-yl)-N-phenylacetamides
In current times, researchers adopted the click chemistry approach for the synthesis of various druglike molecules by using a few reliable, feasible, practical and selective chemical transformations via click formation. In present work, we focussed on the most triazole clubbed thiazolidine-2,4-dione derivatives as the most promising motifs for broad biological application. A total of fifteen (CF-4a-o) derivatives were synthesized and well characterized with various analytical techniques.
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