像拜访老朋友:21世纪的费舍尔糖基化:现代方法和技术

IF 8.6 2区化学 Q1 Chemistry

Topics in Current Chemistry Pub Date : 2022-05-21 DOI:10.1007/s41061-022-00383-9

Matteo Haese, Kai Winterhalter, Jessica Jung, Magnus S. Schmidt

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引用次数: 1

摘要

费舍尔糖基化是单糖和醇在酸性催化剂作用下产生吡喃苷和呋喃苷形式的典型化学反应。这个反应至今仍用于合成特殊的糖苷，自埃米尔·费舍尔在19世纪90年代发现该方法以来，对该方法的优化和修改一直在继续。本文综述了近15年来Fischer糖基化的研究进展及其在现代化学方法中的应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Like Visiting an Old Friend: Fischer Glycosylation in the Twenty-First Century: Modern Methods and Techniques

Fischer glycosylation is typically the chemical reaction of a monosaccharide and an alcohol in presence of an acidic catalyst to afford glycosides in pyranosidic and furanosidic forms. This reaction is still applied today for the synthesis of specialized glycosides, and optimization and modification of the method have continued since its discovery by Emil Fischer in the 1890s. This review presents advancements in Fischer glycosylation described in literature of the past 15 years and its implementation in modern chemical methods.

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来源期刊

Topics in Current Chemistry 化学-化学综合

CiteScore

11.70

自引率

1.20%

发文量

审稿时长

6-12 weeks

期刊介绍： Topics in Current Chemistry provides in-depth analyses and forward-thinking perspectives on the latest advancements in chemical research. This renowned journal encompasses various domains within chemical science and their intersections with biology, medicine, physics, and materials science. Each collection within the journal aims to offer a comprehensive understanding, accessible to both academic and industrial readers, of emerging research in an area that captivates a broader scientific community. In essence, Topics in Current Chemistry illuminates cutting-edge chemical research, fosters interdisciplinary collaboration, and facilitates knowledge-sharing among diverse scientific audiences.