晚期颊癌的激光消融手术

R. Bhalla, S. Bhalla, Duleep D. Bhonsale, D. Pawar
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引用次数: 2

摘要

口腔癌是印度的一个主要健康问题。各种形式的烟草使用使这一问题升级,成为印度男性癌症的主要原因。许多患者因害怕面部损伤而推迟手术,因此出现了晚期颊癌。晚期颊癌的治疗方法很少。传统的手术、化疗和放疗对病人的缓解作用微乎其微。由于野癌术后不可避免的复发,使得手术在控制肿瘤扩散方面是徒劳的。对于不可切除的肿瘤,姑息治疗通常仅限于疼痛控制和通过插入鼻胃管绕过口腔功能。在过去10年中,死亡率一直在变化。因此,这些患者的生活质量已成为大多数癌症论坛讨论的问题。病人痛苦的主要原因是肿瘤很大。病灶内激光消融提供了另一种方法来摧毁大部分肿瘤。肿瘤体积的减小使口腔功能和疼痛得到很好的恢复。本研究共观察49例患者。许多患者在激光消融和化疗后病情得到缓解。结合生活质量和生活数量对结果进行分析,并将所得质量指数应用于患者。大多数患者术后质量指数良好。所有患者对手术都非常满意。患者的生活质量和预期总体生存时间都得到了改善。结论:激光消融为晚期口腔癌的缓解和缓解提供了一种新的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Laser Ablation Surgery in Late Stage Buccal Cancer
Oral cancer is a major health problem in India. The use of tobacco in various forms has escalated the problem to be the leading cause of cancer in males in India. Many patients postpone surgery for fear of facial mutilation and therefore present with Late stage Buccal Cancer. The management of Late stage buccal cancer has very few options. Conventional surgery, chemotherapy and radiation give very little relief to patients. The occurrence of inevitable recurrence after surgery due to Field cancerisation makes the surgery a futile exercise in controlling the spread of the tumor. The treatment in unresectable tumors which is given as palliation is often limited to pain control and bypassing of oral functions by inserting a nasogastric tube. The mortality rate has remained changed over last 10 years. Therefore Quality of life in these patients has become a discussion matter in most cancer forums. The main cause of the suffering of the patient is the bulk of the tumour. Intralesional Laser ablation offers an alternative way to destroy the bulk of the tumor. The reduction in tumor volume allows good restitution of oral function and pain. There were 49 patients observed in this study. Many patients went into remission after laser ablation and Chemotherapy. The ensuing results were analyzed taking into account Quality and Quantity of life and the resulting Quality index was applied on the patients. Most patients had a good Quality Index post-procedure. All patients were highly satisfied with the procedure. There was an enhanced benefit noted in the quality of life and the expected overall survival time of the patients. Conclusion: Laser Ablation offers an alternative treatment in late-stage Oral Cancer for palliation as well as remission.
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