The use of combined laser therapy in treatment of skin papillomatosis

Objective — to compare the effectiveness of combined ablative and non-ablative methods of laser treatment and cryodestruction in patients with widespread papillomatosis. Materials and methods. For treatment we used the Fotona SP Spectro new laser system which has two handpieces — for ablative (wavelength 2940 nm, erbium laser) and non­ablative (neodymium Nd:YAG laser, wavelength 1064 nm) treatment methods, Fotona S11 scanner (neodymium laser, wavelength 1064 nm) and Cry­ac cryospray.Under observation were 45 patients with widespread recurrent papillomatosis, with confirmed papillomavirus infection (ICD10 code D23.5; ICD11 XH17Q9). The lesion area was the front surface of the chest, under the mammary glands, the area of the treatment area — 10 × 10 cm.According to the inclusion and exclusion criteria from the retrospective analysis of the disease histories, three groups of patients were formed: group 1 — treatment according to the accepted method of laser therapy with an erbium (ER:YAG) laser, group 2— combined ablative and non­ablative laser therapy (with erbium and neodymium lasers) and group 3 — cryodestruction of papillomas. Results and discussion. The best result and the speed of the obtained positive results of the treatment and a significantly less frequent occurrence of new elements during the observation within a year after the start of therapy were shown by group 2 — where combined laser therapy was applied. Significant advantages of laser therapy over cryodestruction were determined according to the results of this study and according to the current literature. Conclusions. The combined method of laser therapy, especially the mechanisms of the pathogenesis of the obtained therapeutic effect, require careful study. According to the obtained results, this approach is the most effective in terms of both aesthetic and therapeutic (positive effect on pathogenetic links) achievements.