激光联合治疗在皮肤乳头状瘤病中的应用

Zh.V. Korolova, Е.О. Vasilchuk
{"title":"激光联合治疗在皮肤乳头状瘤病中的应用","authors":"Zh.V. Korolova, Е.О. Vasilchuk","doi":"10.30978/ujdvk2023-2-14","DOIUrl":null,"url":null,"abstract":"Objective — to compare the effectiveness of combined ablative and non-ablative methods of laser treatment and cryodestruction in patients with widespread papillomatosis.\nMaterials and methods. For treatment we used the Fotona SP Spectro new laser system which has two handpieces — for ablative (wavelength 2940 nm, erbium laser) and non­ablative (neodymium Nd:YAG laser, wavelength 1064 nm) treatment methods, Fotona S11 scanner (neodymium laser, wavelength 1064 nm) and Cry­ac cryospray.Under observation were 45 patients with widespread recurrent papillomatosis, with confirmed papillomavirus infection (ICD10 code D23.5; ICD11 XH17Q9). The lesion area was the front surface of the chest, under the mammary glands, the area of the treatment area — 10 × 10 cm.According to the inclusion and exclusion criteria from the retrospective analysis of the disease histories, three groups of patients were formed: group 1 — treatment according to the accepted method of laser therapy with an erbium (ER:YAG) laser, group 2— combined ablative and non­ablative laser therapy (with erbium and neodymium lasers) and group 3 — cryodestruction of papillomas.\nResults and discussion. The best result and the speed of the obtained positive results of the treatment and a significantly less frequent occurrence of new elements during the observation within a year after the start of therapy were shown by group 2 — where combined laser therapy was applied. Significant advantages of laser therapy over cryodestruction were determined according to the results of this study and according to the current literature.\nConclusions. The combined method of laser therapy, especially the mechanisms of the pathogenesis of the obtained therapeutic effect, require careful study. According to the obtained results, this approach is the most effective in terms of both aesthetic and therapeutic (positive effect on pathogenetic links) achievements.","PeriodicalId":23420,"journal":{"name":"Ukrainian Journal of Dermatology, Venerology, Cosmetology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The use of combined laser therapy in treatment of skin papillomatosis\",\"authors\":\"Zh.V. Korolova, Е.О. Vasilchuk\",\"doi\":\"10.30978/ujdvk2023-2-14\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective — to compare the effectiveness of combined ablative and non-ablative methods of laser treatment and cryodestruction in patients with widespread papillomatosis.\\nMaterials and methods. For treatment we used the Fotona SP Spectro new laser system which has two handpieces — for ablative (wavelength 2940 nm, erbium laser) and non­ablative (neodymium Nd:YAG laser, wavelength 1064 nm) treatment methods, Fotona S11 scanner (neodymium laser, wavelength 1064 nm) and Cry­ac cryospray.Under observation were 45 patients with widespread recurrent papillomatosis, with confirmed papillomavirus infection (ICD10 code D23.5; ICD11 XH17Q9). The lesion area was the front surface of the chest, under the mammary glands, the area of the treatment area — 10 × 10 cm.According to the inclusion and exclusion criteria from the retrospective analysis of the disease histories, three groups of patients were formed: group 1 — treatment according to the accepted method of laser therapy with an erbium (ER:YAG) laser, group 2— combined ablative and non­ablative laser therapy (with erbium and neodymium lasers) and group 3 — cryodestruction of papillomas.\\nResults and discussion. The best result and the speed of the obtained positive results of the treatment and a significantly less frequent occurrence of new elements during the observation within a year after the start of therapy were shown by group 2 — where combined laser therapy was applied. Significant advantages of laser therapy over cryodestruction were determined according to the results of this study and according to the current literature.\\nConclusions. The combined method of laser therapy, especially the mechanisms of the pathogenesis of the obtained therapeutic effect, require careful study. According to the obtained results, this approach is the most effective in terms of both aesthetic and therapeutic (positive effect on pathogenetic links) achievements.\",\"PeriodicalId\":23420,\"journal\":{\"name\":\"Ukrainian Journal of Dermatology, Venerology, Cosmetology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ukrainian Journal of Dermatology, Venerology, Cosmetology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.30978/ujdvk2023-2-14\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ukrainian Journal of Dermatology, Venerology, Cosmetology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30978/ujdvk2023-2-14","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

目的:比较激光和冷冻破坏联合消融与非消融治疗广泛性乳头状瘤病的疗效。材料和方法。对于治疗,我们使用了Fotona SP Spectro新型激光系统,该系统有两个机头-用于烧蚀(波长2940 nm,铒激光)和非烧蚀(钕Nd:YAG激光,波长1064 nm)治疗方法,Fotona S11扫描仪(钕激光,波长1064 nm)和Cry-ac冷冻喷雾。观察45例广泛复发性乳头瘤病患者,确诊乳头瘤病毒感染(ICD10代码D23.5;ICD11 XH17Q9)。病变区域为胸部前表面,乳腺下方,治疗区面积- 10 × 10 cm。根据病史回顾性分析的纳入和排除标准,将患者分为三组:1组-按照公认的激光治疗方法使用铒激光(ER:YAG)治疗,2组-消融和非消融激光联合治疗(铒和钕激光),3组-乳头状瘤冷冻破坏。结果和讨论。在治疗开始后一年内的观察中,第2组显示出最好的结果和获得治疗阳性结果的速度,以及新元素出现的频率显着降低-其中应用联合激光治疗。根据本研究的结果和目前的文献,确定了激光治疗相对于冷冻破坏的显著优势。激光联合治疗的方法,特别是所获得的治疗效果的发病机制,需要仔细研究。根据所获得的结果,这种方法在美学和治疗(对发病环节的积极影响)方面都是最有效的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The use of combined laser therapy in treatment of skin papillomatosis
Objective — to compare the effectiveness of combined ablative and non-ablative methods of laser treatment and cryodestruction in patients with widespread papillomatosis. Materials and methods. For treatment we used the Fotona SP Spectro new laser system which has two handpieces — for ablative (wavelength 2940 nm, erbium laser) and non­ablative (neodymium Nd:YAG laser, wavelength 1064 nm) treatment methods, Fotona S11 scanner (neodymium laser, wavelength 1064 nm) and Cry­ac cryospray.Under observation were 45 patients with widespread recurrent papillomatosis, with confirmed papillomavirus infection (ICD10 code D23.5; ICD11 XH17Q9). The lesion area was the front surface of the chest, under the mammary glands, the area of the treatment area — 10 × 10 cm.According to the inclusion and exclusion criteria from the retrospective analysis of the disease histories, three groups of patients were formed: group 1 — treatment according to the accepted method of laser therapy with an erbium (ER:YAG) laser, group 2— combined ablative and non­ablative laser therapy (with erbium and neodymium lasers) and group 3 — cryodestruction of papillomas. Results and discussion. The best result and the speed of the obtained positive results of the treatment and a significantly less frequent occurrence of new elements during the observation within a year after the start of therapy were shown by group 2 — where combined laser therapy was applied. Significant advantages of laser therapy over cryodestruction were determined according to the results of this study and according to the current literature. Conclusions. The combined method of laser therapy, especially the mechanisms of the pathogenesis of the obtained therapeutic effect, require careful study. According to the obtained results, this approach is the most effective in terms of both aesthetic and therapeutic (positive effect on pathogenetic links) achievements.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信