S. Herson MD , C. Lok MD , A. Gérard MD , F. Schooneman MD , J.-C. Roujeau MD , P. Godeau MD
{"title":"血浆置换治疗皮肌炎和多发性肌炎。41个疗程血浆置换的回顾性研究","authors":"S. Herson MD , C. Lok MD , A. Gérard MD , F. Schooneman MD , J.-C. Roujeau MD , P. Godeau MD","doi":"10.1016/S0278-6222(87)80020-7","DOIUrl":null,"url":null,"abstract":"<div><p>The records of 41 courses of plasma exchange (PE) performed in the treatment of 37 patients with dermatomyositis (21) or polymyositis (16) were retrospectively reviewed. In nearly all cases, PE was added to a previously ineffective therapeutic regimen of corticosteroids plus cytotoxic drugs. An improvement in muscle strength was obtained during the PE course in 26 cases (63.4%), especially in diseases with an acute course. Despite their uncontrolled nature, these results confirm the previous publications of P. Dau, suggesting that PE may be of therapeutic value in dermatomyositis and polymyositis.</p></div>","PeriodicalId":101030,"journal":{"name":"Plasma Therapy and Transfusion Technology","volume":"8 2","pages":"Pages 127-130"},"PeriodicalIF":0.0000,"publicationDate":"1987-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0278-6222(87)80020-7","citationCount":"6","resultStr":"{\"title\":\"Plasma exchange for dermatomyositis and polymyositis. Retrospective study of 41 courses of plasma exchange\",\"authors\":\"S. Herson MD , C. Lok MD , A. Gérard MD , F. Schooneman MD , J.-C. Roujeau MD , P. Godeau MD\",\"doi\":\"10.1016/S0278-6222(87)80020-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The records of 41 courses of plasma exchange (PE) performed in the treatment of 37 patients with dermatomyositis (21) or polymyositis (16) were retrospectively reviewed. In nearly all cases, PE was added to a previously ineffective therapeutic regimen of corticosteroids plus cytotoxic drugs. An improvement in muscle strength was obtained during the PE course in 26 cases (63.4%), especially in diseases with an acute course. Despite their uncontrolled nature, these results confirm the previous publications of P. Dau, suggesting that PE may be of therapeutic value in dermatomyositis and polymyositis.</p></div>\",\"PeriodicalId\":101030,\"journal\":{\"name\":\"Plasma Therapy and Transfusion Technology\",\"volume\":\"8 2\",\"pages\":\"Pages 127-130\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1987-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0278-6222(87)80020-7\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Plasma Therapy and Transfusion Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0278622287800207\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plasma Therapy and Transfusion Technology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0278622287800207","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Plasma exchange for dermatomyositis and polymyositis. Retrospective study of 41 courses of plasma exchange
The records of 41 courses of plasma exchange (PE) performed in the treatment of 37 patients with dermatomyositis (21) or polymyositis (16) were retrospectively reviewed. In nearly all cases, PE was added to a previously ineffective therapeutic regimen of corticosteroids plus cytotoxic drugs. An improvement in muscle strength was obtained during the PE course in 26 cases (63.4%), especially in diseases with an acute course. Despite their uncontrolled nature, these results confirm the previous publications of P. Dau, suggesting that PE may be of therapeutic value in dermatomyositis and polymyositis.