Overweight and comorbidity in patients with malignant tumors of the abdominal organs

The aim – to establish the clinical and pathogenetic significance of overweight and comorbidity in patients with malignant neoplasms (MN) of the abdominal cavity. Material and methods. The study was performed on the basis of the Chernivtsi Regional Clinical Oncology Centre and the Oncology Clinic of Bukovinian State Medical University and covered observation materials of 50 patients with intra-abdominal neoplasms. Among them, 35 individualsforming the main group were obese (body mass index ≥30), the rest formed the comparison group. Comorbidity index, risk complication ratio, confidence intervals, Fisher (P) and χ2 coefficients were calculated according to Yates and Pearson. Results. In the comparison group, comorbidities were detected in only 6 patients (40.0%), in the main group, comorbidities were detected in all patients. The value of the comorbidity index in the main group was 11.23±0.98 against 6.37±0.72 (P=0.005). The risk of complications increases significantly in the presence of obesity (OR+ 2.49, min-1.29, max-4.80). The term of hospitalization increases slightly (22.36±3.14 in the main group, against 16.73±2.50 in the comparison group, P=0.18). Conclusions. In patients with malignant neoplasms of the abdominal cavity, the risk of postoperative complications is 1.29-6.96 times higher than in the absence of obesity. The presence of obesity is a significant factor in aggravating the condition, prolongs the period of hospitalization of patients with malignant neoplasms, creates additional challenges for the oncologist.