离心微流控平台上海藻酸盐微球的制备

2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS) Pub Date : 2007-01-01 DOI:10.1109/MEMSYS.2007.4433113

S. Haeberle, L. Naegele, R. Burger, R. Zengerle, J. Ducrée

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引用次数: 10

摘要

我们提出了一种利用聚合物管微喷嘴直接、离心诱导制备海藻酸盐小珠的新方法，这些小珠的直径在180 - 800微米之间可调节。主峰的大小分布CV值为7 - 16%。每秒多达600颗珠子和通道从微喷嘴通过气隙向标准实验室管(“epi”)发出，该管连接在旋转的转子上，并含有固化剂。在5赫兹和28赫兹之间的旋转频率，管对齐水平下旋转，并返回到垂直位置，只要转子是在休息。硬化的珠子被收集在管内，以便进一步处理或表征。该方法被认为是一种低成本的微封装技术。

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Alginate micro-bead fabrication on a centrifugal microfluidics platform

We present a novel method for the direct, centrifugally induced fabrication of small alginate beads displaying adjustable diameters between 180 mum and 800 mum by polymer-tube micronozzles. The size distribution features a CV of 7 - 16 % for the main peak. Up to 600 beads per second and channel are issued from the micronozzle through an air gap towards a standard lab tube ("Eppi") attached to the rotor spinning and containing a curing agent. At spinning frequencies between 5 Hz and 28 Hz, the tubes align horizontally under rotation and return to a vertical position as soon as the rotor is at rest. The hardened beads are collected within the tube for further processing or characterization. This method is considered as a low cost technology for micro encapsulation technologies.

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来源期刊

2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS)

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