减少吸收剂量比的乳房放射治疗的新畸形大纲

A. Khorshidi, M. Ashoor
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引用次数: 1

摘要

乳腺癌是女性最常见的恶性疾病之一。肿瘤肿块手术后,放射治疗通常被认为是治疗的金标准。千至兆电压光子由于其特有的深度剂量积累机制而被提出,将乳房皮肤的剂量减少到最大剂量暴露的一小部分。在治疗期间,平均腺体剂量通常被用作识别辐射风险的标准。本文采用蒙特卡罗模拟方法,对立方矩形(CR)和圆柱锥形(CT)两种轮廓进行了建模,并进行了相应的假设,并通过511 keV能量的正电子源,比较了记录的吸收剂量比(ADR)值。结果表明,随着CR轮廓高度的降低,ADR量旁边的吸收和散射截面的量减小。CR轮廓图的平均剂量比量较CT轮廓图降低约96%。通过增加正电子源与乳头的距离,两个轮廓的不良反应量都减少了。累积剂量比的量在CR轮廓上明显下降,而在CT轮廓上明显下降。本研究可用于检查乳腺组织畸形的治疗计划。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
New Deformity Outline on the Breast Radiation Therapy for diminishing Absorbed Dose Ratio
Breast cancer is one of the most common malignant diseases in women. After tumor mass surgery, radiation therapy is regularly taken into account the gold standard for the treatment. Kilo to Mega voltage photons have been suggested due to their characteristic depth dose build-up regime, reducing the dose to the breast skin to a fraction of the maximum dose exposure. During treatment, mean glandular dose is commonly used as a criterion for identifying radiation risks. Here, two outlines in cubic-rectangular (CR) and cylindrical- taper (CT) outlines were modelled together with corresponding assumptions using Monte-Carlo simulation and the recorded absorbed dose ratio (ADR) values were compared via defined a positron source by 511 keV energy. The results showed that the amounts of absorption and scattering cross-sections next to the ADR amount decreased as the height of the CR outline decreased. The average dose ratio amount in the CR outline was reduced by about 96% compared to that in the CT outline. By increasing the positron source distance from the nipple, the ADR amounts decreased for both outlines. The amount of accumulated dose ratio decreased harshly in the CR outline rather than in the CT outline. This study can be useful to examine breast tissue deformity in treatment planning.
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