{"title":"多孔硅纳米颗粒制备方法的改进及其抗氧化、抗癌活性的发展策略","authors":"Kareem H. Jawad, Butheina Hasson","doi":"10.53293/jasn.2021.3890.1054","DOIUrl":null,"url":null,"abstract":"*Corresponding Author: Butheina A. Hasson 100235@uotechnology.edu.iq Abstract Porous silicon nanoparticles, or PSNPs, are one of the most common NPS with distinct characteristics. PSNPs were created using an enhanced approach known as the electrochemical etching process. The nanoparticles were treated with a post-laser to obtain the nanoparticles, which were subsequently analyzed using (SEM), (UV-Vis), and (XRD). The size refers to porous silicon with a nanostructure. Because of the differences in interaction between the HF electrolyzed and silicon and crystal structure, PS (100) offers better NP properties than directional silicon (111). PSNPs' antioxidant activity was measured using the DPPH test, while cytotoxicity was measured using the MTT assay on Hella cells. PSNPs have an inhibitory impact on cancer cell growth and antioxidants, according to the findings. PSNPs did not have any toxicological effects on the skin, lungs, or spleen after injection.","PeriodicalId":15241,"journal":{"name":"Journal of Applied Sciences and Nanotechnology","volume":"93 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"7","resultStr":"{\"title\":\"Developing Strategy for a Successful Antioxidant, Anticancer Activity via an Improved Method Prepared to Porous Silicon Nanoparticles\",\"authors\":\"Kareem H. Jawad, Butheina Hasson\",\"doi\":\"10.53293/jasn.2021.3890.1054\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"*Corresponding Author: Butheina A. Hasson 100235@uotechnology.edu.iq Abstract Porous silicon nanoparticles, or PSNPs, are one of the most common NPS with distinct characteristics. PSNPs were created using an enhanced approach known as the electrochemical etching process. The nanoparticles were treated with a post-laser to obtain the nanoparticles, which were subsequently analyzed using (SEM), (UV-Vis), and (XRD). The size refers to porous silicon with a nanostructure. Because of the differences in interaction between the HF electrolyzed and silicon and crystal structure, PS (100) offers better NP properties than directional silicon (111). PSNPs' antioxidant activity was measured using the DPPH test, while cytotoxicity was measured using the MTT assay on Hella cells. PSNPs have an inhibitory impact on cancer cell growth and antioxidants, according to the findings. PSNPs did not have any toxicological effects on the skin, lungs, or spleen after injection.\",\"PeriodicalId\":15241,\"journal\":{\"name\":\"Journal of Applied Sciences and Nanotechnology\",\"volume\":\"93 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"7\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Applied Sciences and Nanotechnology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.53293/jasn.2021.3890.1054\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Applied Sciences and Nanotechnology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.53293/jasn.2021.3890.1054","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
摘要
*通讯作者:Butheina A. Hasson 100235@uotechnology.edu.iq摘要多孔硅纳米粒子(Porous silicon nanoparticles, PSNPs)是最常见的纳米粒子之一,具有不同的特性。PSNPs是使用一种被称为电化学蚀刻工艺的增强方法创建的。采用后激光处理得到纳米颗粒,随后使用(SEM)、(UV-Vis)和(XRD)对纳米颗粒进行分析。尺寸是指具有纳米结构的多孔硅。由于电解的HF与硅之间的相互作用和晶体结构的差异,PS(100)比定向硅(111)具有更好的NP性能。采用DPPH法测定PSNPs的抗氧化活性,采用MTT法测定细胞毒性。根据研究结果,psnp对癌细胞生长和抗氧化剂有抑制作用。注射后,psnp对皮肤、肺和脾脏没有任何毒理学影响。
Developing Strategy for a Successful Antioxidant, Anticancer Activity via an Improved Method Prepared to Porous Silicon Nanoparticles
*Corresponding Author: Butheina A. Hasson 100235@uotechnology.edu.iq Abstract Porous silicon nanoparticles, or PSNPs, are one of the most common NPS with distinct characteristics. PSNPs were created using an enhanced approach known as the electrochemical etching process. The nanoparticles were treated with a post-laser to obtain the nanoparticles, which were subsequently analyzed using (SEM), (UV-Vis), and (XRD). The size refers to porous silicon with a nanostructure. Because of the differences in interaction between the HF electrolyzed and silicon and crystal structure, PS (100) offers better NP properties than directional silicon (111). PSNPs' antioxidant activity was measured using the DPPH test, while cytotoxicity was measured using the MTT assay on Hella cells. PSNPs have an inhibitory impact on cancer cell growth and antioxidants, according to the findings. PSNPs did not have any toxicological effects on the skin, lungs, or spleen after injection.