复发性家族性疖病与潘通-瓦伦丁白细胞素阳性甲氧西林敏感金黄色葡萄球菌ST1相关

Q3 Medicine

Pediatric Infection and Vaccine Pub Date : 2018-08-01 DOI:10.14776/PIV.2018.25.E6

Jin Young Lee, Jiyoon Park, I. K. Bae, Seri Jeong, Ji Hyun Park, Sol Jin

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引用次数: 3

摘要

金黄色葡萄球菌现在是世界范围内主要的社区获得性病原体，特别是与皮肤和软组织感染有关。葡萄球菌以定植菌或家庭环境污染物的形式存在，增加了复发感染的风险。我们描述了韩国由潘通-瓦伦丁白细胞素阳性甲氧西林敏感金黄色葡萄球菌ST1引起的复发性家族性疖病。一个婴儿，他的父亲和母亲因甲氧西林敏感金黄色葡萄球菌(MSSA)感染而患有疖病，具有相同的敏感性模式。3株分离株均为ST1型，均为agr i型，PCR检测到sec和seh，均含有pton - valentine leukocidin (PVL)基因。金黄色葡萄球菌家庭传播的危险因素包括皮肤状况和家庭成员之间的密切身体接触。家庭接触者金黄色葡萄球菌定殖与金黄色葡萄球菌感染发生的关系有待进一步研究。

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Recurrent Familial Furunculosis Associated with Panton-Valentine Leukocidin-Positive Methicillin-Susceptible Staphylococcus aureus ST1

Staphylococcus aureus is now a major community-acquired pathogen worldwide, notably associated with skin and soft tissue infections. Staphylococci are present in the form of colonizers or environmental contaminants at home and increase the risk of recurrent infection. We are describing recurrent familial furunculosis caused by Panton-Valentine Leukocidin-positive methicillin susceptible S. aureus ST1 in Korea. An infant, his father and mother had furunculosis due to methicillin-sensitive S. aureus (MSSA) infection with identical susceptibility patterns. ST1 accounted for all 3 isolates and they were confirmed of having agr group I. Both sec and seh were detected in all isolates using polymerase chain reaction (PCR) assays, and all isolates contained Panton-Valentine leukocidin (PVL) genes. Risk factors for the household spread of S. aureus include skin conditions and close physical contact among household members. The relationship between S. aureus colonization of household contacts and the occurrence of S. aureus infection should be studied into more detail.

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来源期刊

Pediatric Infection and Vaccine Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： Pediatric Infection and Vaccine is an official publication of the Korean Society of Pediatric Infectious Diseases and a peer-reviewed, open-access, multidisciplinary journal directed to physicians and other health care professionals who manage infectious diseases of childhood. The editorial board calls for the articles that originate from worldwide research or clinical study groups and the publication is determined by the editors and reviewers who are the experts in the specific field of infectious diseases of childhood. The categories of manuscripts are original articles, case reports, reviews and rapid communication. The Journal is published triannually and distributed to members of the Korean Society of Pediatric Infectious Diseases, medical schools, libraries and related institutes to persue the academic advancement in infectious diseases and to promote active communication between the members and international societies of pediatric infectious diseases. Eventually, the journal aims to contribute to the cure of infectious diseases of childhood and to the improvement of public health.