{"title":"抗癌纳米药物传递13c -编辑/ 13c -过滤传递动态15N{1H} NOE测量用于研究短非线性基元的DNA/RNA相互作用:研究牙龈癌细胞DNA/RNA动力学的现代工具","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000365","DOIUrl":null,"url":null,"abstract":"In the current work, the anti–cancer Nano drug delivery 13C–edited/13C–filtered transferred dynamic 15N{1H} NOE measurements for studying DNA/RNA interactions with short non–linear motifs as a modern tool for studying DNA/RNA dynamics in gum cancer cells are studied. While improvements in screening have enabled the early diagnoses of many gum cancers, the significant number of diagnoses that eventually lead to death (~20% at 15 years) provide the primary impetus for advances in surgical intervention.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"25 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"11","resultStr":"{\"title\":\"The anti–cancer nano drug delivery 13C–edited/13C–filtered transferred dynamic 15N{1H} NOE measurements for studying DNA/RNA interactions with short non–linear motifs: A modern tool for studying DNA/RNA dynamics in gum cancer cells\",\"authors\":\"A. Heidari, R. Gobato\",\"doi\":\"10.15761/DOMR.1000365\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the current work, the anti–cancer Nano drug delivery 13C–edited/13C–filtered transferred dynamic 15N{1H} NOE measurements for studying DNA/RNA interactions with short non–linear motifs as a modern tool for studying DNA/RNA dynamics in gum cancer cells are studied. While improvements in screening have enabled the early diagnoses of many gum cancers, the significant number of diagnoses that eventually lead to death (~20% at 15 years) provide the primary impetus for advances in surgical intervention.\",\"PeriodicalId\":10996,\"journal\":{\"name\":\"Dental, Oral and Maxillofacial Research\",\"volume\":\"25 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"11\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dental, Oral and Maxillofacial Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15761/DOMR.1000365\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dental, Oral and Maxillofacial Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/DOMR.1000365","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The anti–cancer nano drug delivery 13C–edited/13C–filtered transferred dynamic 15N{1H} NOE measurements for studying DNA/RNA interactions with short non–linear motifs: A modern tool for studying DNA/RNA dynamics in gum cancer cells
In the current work, the anti–cancer Nano drug delivery 13C–edited/13C–filtered transferred dynamic 15N{1H} NOE measurements for studying DNA/RNA interactions with short non–linear motifs as a modern tool for studying DNA/RNA dynamics in gum cancer cells are studied. While improvements in screening have enabled the early diagnoses of many gum cancers, the significant number of diagnoses that eventually lead to death (~20% at 15 years) provide the primary impetus for advances in surgical intervention.