新的羽扇豆型三萜

P. Mkounga, H. L. Maza, B. M. Ouahouo, Lydie N Tyon, H. Ishikawa, H. Nishino, A. Nkengfack
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引用次数: 6

摘要

摘要/ Abstract摘要:从生长在manhot esculenta上的半寄生植物globimetulei (Loranthaceae)的茎中分离得到了3个新的羽豆型三萜衍生物globimetulin A(1)、B(2)和C(3),以及5个已知化合物。通过质谱、红外光谱、一维和二维核磁共振数据和化学证据对新化合物的结构进行了详细的分析,并对化合物的结构进行了鉴定。其中一些化合物在体外对多种微生物的抑菌活性进行了评估,但没有一种化合物表现出明显的活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
New lupan-type triterpenoids
Abstract Three new lupan-type triterpernoid derivatives, namely globimetulin A (1), B (2) and C (3), were isolated from the shoot of Globimetula dinklagei (Loranthaceae), a hemiparasitic plant growing on Manihot esculenta, along with five known compounds: friedelin (4), friedelan-3-ol (5), 28-hydroxyfriedelin (6), 4-hydroxy-3,5-dimethoxybenzoic acid (7) and (1R,5S,7S)-7-[2-(4-hydroxyphenyl)ethyl]-2,6-dioxabicyclo[3.3.1]nonan-3-one (8). The structures of the new compounds were elucidated by detailed analyses of their MS, IR, 1D and 2D NMR spectral data and chemical evidence. Some of these compounds were evaluated in vitro for their antimicrobial activities against a wide range of microorganisms, but none of them exhibited noticeable activity.
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