伊拉克人感染新冠病毒的危险因素和一些生物标志物参数测定

R. Salih, A. Taha, N. Mohamed
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摘要

Covid-19是一项全球性挑战,将医疗保健推向极限。确定了与严重或致命疾病病程风险增加相关的生物学参数,包括与健康状况不佳、器官损伤和凝血功能障碍相关的条件。在最近的一项研究中,考虑了年龄、性别、血型(ABO)、吸烟以及白细胞、淋巴细胞、c反应蛋白(CRP)、铁蛋白、d -二聚体和钾水平等生物标志物等风险因素。根据世界卫生组织(卫生组织)的建议,从伊拉克病人身上收集了100份鼻咽拭子和血液样本,并根据疾病的严重程度分为五组:无症状、轻度、中度、严重和死亡。目前的研究是基于风险因素及其对疾病严重程度的影响(年龄、性别、血型和吸烟)。因此,年龄增长与疾病严重程度增加之间存在显著的正线性联系(R2=0.91)。研究结果显示,男性和女性感染SARS-CoV-2的人数差异有统计学意义。有趣的是,男性比女性更容易受到感染。此外,由于O型血在中东人口中比其他血型分布更广泛,因此O型血的人更容易受到感染。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Determination of Risk Factors and Some Biomarkers Parameters during Infected Iraqis with Covid-19
Covid-19 is a global challenge that drives health care to its limits. Biological parameters associated with increased risk of severe or fatal disease courses were identified, including conditions connected with a poor state of health, organ damage, and coagulation dysfunction. In a recent study, risk factors like age, sex, blood group (ABO), smoking, and several biomarkers like white blood cells, lymphocytes, C-reactive protein (CRP), ferritin, D-dimer, and potassium level were considered. One hundred nasopharyngeal swabs and blood samples were collected from Iraqi patients and classified according to the severity of the disease into five groups: Asymptomatic, Mild, Moderate, Severe, and Deceased, according to the recommendations of the World Health Organization (WHO). The current study was based on the risk factors and their effect on disease severity (age, sex, blood type, and smoking). As a result, there was a substantial positive linear link (R2=0.91) between getting older and increasing disease severity. Study results were showed a little statistically significant difference in the number of males and females infected with SARS-CoV-2. Interestingly, males were shown to be more susceptible to infection than females. Also, because type (O) blood is more extensively distributed in the Middle East population than the other blood types, those with type (O) blood are more susceptible to infection.
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