{"title":"认知灵活性、认知回避和焦虑介导的MS患者行为-脑系统与抑郁的关系","authors":"","doi":"10.32592/nkums.15.2.40","DOIUrl":null,"url":null,"abstract":"Introduction: This study aimed to investigate the depression of MS patients based on behavioral-brain systems mediated by cognitive flexibility, cognitive avoidance, and anxiety in the form of a causal model.\nMethod: The present study was a descriptive-correlational study using structural equation modeling. The statistical population included all MS patients in Mashhad, Iran. Considering 20 people for each parameter of the model, 300 people were selected according to the suggestion of Schuman, Bolton, and Short (2017), which increased to 350 people by the cluster random sampling method due to the possibility of dropout. Data were collected through standard tools: Beck depression (1972), Carver and White (1994) behavioral-brain system, cognitive flexibility of Dennis Wonderwall (2010), Sexton and Dougas (2004) cognitive avoidance, and Pennsylvania concern. The structural modeling method and AMOS software (version 21) were used to analyze the results.\nResults: The results showed that the activating behavioral-brain system and cognitive flexibility had a negative and significant relationship with depression in MS cases. Moreover, the inhibitory behavioral-brain system, cognitive avoidance, and anxiety had a positive and significant relationship with depression. The standardized indirect effect of activating behavioral systems on depression was also significant, and the inhibitory system had a significant indirect effect on cognitive flexibility, cognitive avoidance, and anxiety. The activating behavioral system can negatively predict depression, and the inhibitory behavioral system can positively predict depression.\nConclusion: According to the findings, behavioral-brain systems can predict 0.36 of depressive changes in MS patients due to cognitive flexibility, cognitive avoidance, and anxiety.","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"18 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Relationship between Behavioral-Brain Systems and Depression in Patients with MS Mediated by Cognitive Flexibility, Cognitive Avoidance, and Anxiety\",\"authors\":\"\",\"doi\":\"10.32592/nkums.15.2.40\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: This study aimed to investigate the depression of MS patients based on behavioral-brain systems mediated by cognitive flexibility, cognitive avoidance, and anxiety in the form of a causal model.\\nMethod: The present study was a descriptive-correlational study using structural equation modeling. The statistical population included all MS patients in Mashhad, Iran. Considering 20 people for each parameter of the model, 300 people were selected according to the suggestion of Schuman, Bolton, and Short (2017), which increased to 350 people by the cluster random sampling method due to the possibility of dropout. Data were collected through standard tools: Beck depression (1972), Carver and White (1994) behavioral-brain system, cognitive flexibility of Dennis Wonderwall (2010), Sexton and Dougas (2004) cognitive avoidance, and Pennsylvania concern. The structural modeling method and AMOS software (version 21) were used to analyze the results.\\nResults: The results showed that the activating behavioral-brain system and cognitive flexibility had a negative and significant relationship with depression in MS cases. Moreover, the inhibitory behavioral-brain system, cognitive avoidance, and anxiety had a positive and significant relationship with depression. The standardized indirect effect of activating behavioral systems on depression was also significant, and the inhibitory system had a significant indirect effect on cognitive flexibility, cognitive avoidance, and anxiety. The activating behavioral system can negatively predict depression, and the inhibitory behavioral system can positively predict depression.\\nConclusion: According to the findings, behavioral-brain systems can predict 0.36 of depressive changes in MS patients due to cognitive flexibility, cognitive avoidance, and anxiety.\",\"PeriodicalId\":16423,\"journal\":{\"name\":\"journal of north khorasan university of medical sciences\",\"volume\":\"18 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-04-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"journal of north khorasan university of medical sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32592/nkums.15.2.40\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"journal of north khorasan university of medical sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32592/nkums.15.2.40","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
本研究旨在以因果模型的形式探讨由认知灵活性、认知回避和焦虑介导的行为-脑系统对MS患者抑郁的影响。方法:采用结构方程模型进行描述性相关研究。统计人群包括伊朗马什哈德的所有MS患者。考虑到模型的每个参数20人,根据Schuman, Bolton, and Short(2017)的建议选择了300人,考虑到可能出现dropout,采用整群随机抽样的方法增加到350人。通过标准工具收集数据:Beck抑郁症(1972)、Carver和White(1994)行为脑系统、Dennis Wonderwall的认知灵活性(2010)、Sexton和Dougas(2004)认知回避和Pennsylvania关注。采用结构建模方法和AMOS软件(version 21)对结果进行分析。结果:MS患者的行为-脑系统激活和认知灵活性与抑郁呈显著负相关。抑制性行为-脑系统、认知回避和焦虑与抑郁呈显著正相关。激活行为系统对抑郁的标准化间接效应显著,抑制系统对认知灵活性、认知回避和焦虑的间接效应显著。激活行为系统能负向预测抑郁,抑制行为系统能正向预测抑郁。结论:根据研究结果,行为-脑系统可以预测0.36%的MS患者因认知灵活性、认知回避和焦虑引起的抑郁变化。
Relationship between Behavioral-Brain Systems and Depression in Patients with MS Mediated by Cognitive Flexibility, Cognitive Avoidance, and Anxiety
Introduction: This study aimed to investigate the depression of MS patients based on behavioral-brain systems mediated by cognitive flexibility, cognitive avoidance, and anxiety in the form of a causal model.
Method: The present study was a descriptive-correlational study using structural equation modeling. The statistical population included all MS patients in Mashhad, Iran. Considering 20 people for each parameter of the model, 300 people were selected according to the suggestion of Schuman, Bolton, and Short (2017), which increased to 350 people by the cluster random sampling method due to the possibility of dropout. Data were collected through standard tools: Beck depression (1972), Carver and White (1994) behavioral-brain system, cognitive flexibility of Dennis Wonderwall (2010), Sexton and Dougas (2004) cognitive avoidance, and Pennsylvania concern. The structural modeling method and AMOS software (version 21) were used to analyze the results.
Results: The results showed that the activating behavioral-brain system and cognitive flexibility had a negative and significant relationship with depression in MS cases. Moreover, the inhibitory behavioral-brain system, cognitive avoidance, and anxiety had a positive and significant relationship with depression. The standardized indirect effect of activating behavioral systems on depression was also significant, and the inhibitory system had a significant indirect effect on cognitive flexibility, cognitive avoidance, and anxiety. The activating behavioral system can negatively predict depression, and the inhibitory behavioral system can positively predict depression.
Conclusion: According to the findings, behavioral-brain systems can predict 0.36 of depressive changes in MS patients due to cognitive flexibility, cognitive avoidance, and anxiety.