偶发性膀胱平滑肌瘤:基于术前磁共振成像发现的一种成功的长期保守治疗

T. Prayer-Galetti, E. Scagliori, R. Stramare, A. Tregnaghi, F. Moro, F. Zattoni, M. Gardiman, M. Soligo
{"title":"偶发性膀胱平滑肌瘤:基于术前磁共振成像发现的一种成功的长期保守治疗","authors":"T. Prayer-Galetti, E. Scagliori, R. Stramare, A. Tregnaghi, F. Moro, F. Zattoni, M. Gardiman, M. Soligo","doi":"10.31021/jcro.20181116","DOIUrl":null,"url":null,"abstract":"Background: Leiomyomas are benign mesenchymal neoplasms which rarely occur in the urinary bladder, accounting for just 0.43% of all bladder tumours. Due to the paucity of data, very little is known about diagnosis, treatment and follow-up. Thus, despite their nonmalignant nature, they may be considered a true therapeutic challenge. Objective: Conservative management is paramount when assessing and managing benign neoplasms. It is the responsibility of the surgeon to tailor the most appropriate surgery for each patient, finding the best balance between oncologic and functional outcomes and future quality of life. Case report: We present a case report of a patient who was incidentally diagnosed with a large, asymptomatic intramural leiomyoma of the urinary bladder. Following abdominal imaging, biopsy specimens were obtained through cystoscopy, and a transurethral resection of the bladder (TURB) was eventually performed. Imaging findings including Ultrasonography (US), triple-phase Computed Tomography Urography (CTU) and Magnetic Resonance Urography (MRU) are reported, and the most representative images are shown. The patient has been successfully managed with staged TURB and then close outpatient follow-up, and she is currently recurrence-free 8 years after the last endoscopic treatment. Conclusion: Despite the benign nature of leiomyomas, the surgical options for these tumours range from TURB to radical cystectomy. Here, we underline how a conservative approach may be successful regardless of the size and site of the lesion, thus preserving the bladder and the patient’s quality of life without affecting the oncologic outcomes.","PeriodicalId":92396,"journal":{"name":"Journal of cancer research and oncobiology","volume":"55 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Incidental Urinary Bladder Leiomyoma: A Successful Long Term Conservative Treatment Based on Pre-operatory Magnetic Resonance Imaging Findingsr\",\"authors\":\"T. Prayer-Galetti, E. Scagliori, R. Stramare, A. Tregnaghi, F. Moro, F. Zattoni, M. Gardiman, M. Soligo\",\"doi\":\"10.31021/jcro.20181116\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Leiomyomas are benign mesenchymal neoplasms which rarely occur in the urinary bladder, accounting for just 0.43% of all bladder tumours. Due to the paucity of data, very little is known about diagnosis, treatment and follow-up. Thus, despite their nonmalignant nature, they may be considered a true therapeutic challenge. Objective: Conservative management is paramount when assessing and managing benign neoplasms. It is the responsibility of the surgeon to tailor the most appropriate surgery for each patient, finding the best balance between oncologic and functional outcomes and future quality of life. Case report: We present a case report of a patient who was incidentally diagnosed with a large, asymptomatic intramural leiomyoma of the urinary bladder. Following abdominal imaging, biopsy specimens were obtained through cystoscopy, and a transurethral resection of the bladder (TURB) was eventually performed. Imaging findings including Ultrasonography (US), triple-phase Computed Tomography Urography (CTU) and Magnetic Resonance Urography (MRU) are reported, and the most representative images are shown. The patient has been successfully managed with staged TURB and then close outpatient follow-up, and she is currently recurrence-free 8 years after the last endoscopic treatment. Conclusion: Despite the benign nature of leiomyomas, the surgical options for these tumours range from TURB to radical cystectomy. Here, we underline how a conservative approach may be successful regardless of the size and site of the lesion, thus preserving the bladder and the patient’s quality of life without affecting the oncologic outcomes.\",\"PeriodicalId\":92396,\"journal\":{\"name\":\"Journal of cancer research and oncobiology\",\"volume\":\"55 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-11-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of cancer research and oncobiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31021/jcro.20181116\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of cancer research and oncobiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31021/jcro.20181116","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

背景:平滑肌瘤是一种少见的良性膀胱间质肿瘤,仅占膀胱肿瘤的0.43%。由于缺乏数据,对诊断、治疗和随访知之甚少。因此,尽管它们是非恶性的,但它们可能被认为是真正的治疗挑战。目的:在评估和治疗良性肿瘤时,保守治疗是至关重要的。外科医生有责任为每位患者量身定制最合适的手术,在肿瘤和功能结果以及未来生活质量之间找到最佳平衡。病例报告:我们提出一个病例报告的病人谁是偶然诊断为一个大的,无症状的膀胱壁内平滑肌瘤。腹部成像后,通过膀胱镜获得活检标本,最终行经尿道膀胱切除术(TURB)。影像学表现包括超声(US),三相计算机断层尿路造影(CTU)和磁共振尿路造影(MRU),并显示了最具代表性的图像。该患者已成功地进行了分期TURB治疗,然后进行了密切的门诊随访,在最后一次内镜治疗后8年无复发。结论:尽管平滑肌瘤的本质是良性的,但这些肿瘤的手术选择范围从TURB到根治性膀胱切除术。在这里,我们强调无论病变的大小和部位如何,保守入路都可能成功,从而在不影响肿瘤预后的情况下保留膀胱和患者的生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Incidental Urinary Bladder Leiomyoma: A Successful Long Term Conservative Treatment Based on Pre-operatory Magnetic Resonance Imaging Findingsr
Background: Leiomyomas are benign mesenchymal neoplasms which rarely occur in the urinary bladder, accounting for just 0.43% of all bladder tumours. Due to the paucity of data, very little is known about diagnosis, treatment and follow-up. Thus, despite their nonmalignant nature, they may be considered a true therapeutic challenge. Objective: Conservative management is paramount when assessing and managing benign neoplasms. It is the responsibility of the surgeon to tailor the most appropriate surgery for each patient, finding the best balance between oncologic and functional outcomes and future quality of life. Case report: We present a case report of a patient who was incidentally diagnosed with a large, asymptomatic intramural leiomyoma of the urinary bladder. Following abdominal imaging, biopsy specimens were obtained through cystoscopy, and a transurethral resection of the bladder (TURB) was eventually performed. Imaging findings including Ultrasonography (US), triple-phase Computed Tomography Urography (CTU) and Magnetic Resonance Urography (MRU) are reported, and the most representative images are shown. The patient has been successfully managed with staged TURB and then close outpatient follow-up, and she is currently recurrence-free 8 years after the last endoscopic treatment. Conclusion: Despite the benign nature of leiomyomas, the surgical options for these tumours range from TURB to radical cystectomy. Here, we underline how a conservative approach may be successful regardless of the size and site of the lesion, thus preserving the bladder and the patient’s quality of life without affecting the oncologic outcomes.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信