老年人添加糖摄入量与跌倒风险:老年人- enrica队列研究

Ballesteros Jm, Struijk E, Machado-Fragua Md, Ortolá R, R. F., Lopez Garcia
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摘要

背景:添加糖的摄入是几种慢性疾病发展的关键因素。我们的目的是调查老年男性和女性中添加糖摄入量与跌倒风险之间的潜在关联。方法:我们分析了来自senior - enrica队列的2154名年龄≥65岁的西班牙成年人的数据。收集了2008-2010年的基线食物消费量,并确定了有效的饮食历史,其中155种食物被确定含有添加糖。截至2015年,已确定发生跌伤。采用Cox模型进行分析,校正潜在混杂因素,包括营养状况、慢性疾病和睡眠药物。结果:在7.2年的随访中,605名参与者经历了≥1次跌倒,527名参与者遭受了伤害性跌倒。添加糖摄入量≥1的风险比(95%置信区间)分别为:1.0、1.09(0.83-1.42)、1.07(0.82-1.40)、1.15(0.88-1.52)和1.48 (1.12-1.96);p-trend 0.03。相应的伤害性跌倒数字分别为:1.0、1.17(0.88 ~ 1.56)、1.06(0.79 ~ 1.41)、1.13(0.84 ~ 1.52)、1.40 (1.03 ~ 1.90);p-trend 0.10。这些关联没有因年龄、蛋白质、钙或维生素摄入量、饮食质量、体育活动或饮酒而变化。当分别检查添加糖的固体和液体来源时,没有发现差异。结论:老年人摄入添加糖与较高的跌倒风险相关。这增加了支持干预措施减少添加糖摄入量的证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Added Sugar Intake and Risk of Falling Among Older People: The Seniors-ENRICA Cohort Study
Background: Added sugar intake is a key contributor to the development of several chronic diseases. We aimed to investigate the prospective association between added sugar intake and the risk of falling among older men and women. Methods: We analyzed data from 2,154 Spanish adults aged ≥65 years from the Seniors-ENRICA cohort. Baseline food consumption was collected in 2008-2010 with a validated diet history, in which 155 foods were identified to contain added sugar. The occurrence of falls was ascertained up to 2015. Analyses were conducted with Cox models adjusted for potential confounders, including nutritional status, chronic diseases and sleeping medication. Results: Over 7.2y of follow-up, 605 participants experienced ≥1 fall and 527 suffered injurious falls. The hazard ratios (95% confidence interval) for ≥1 fall across quintiles of added sugar intake were: 1.0, 1.09 (0.83-1.42), 1.07 (0.82-1.40), 1.15 (0.88-1.52), and 1.48 (1.12-1.96); p-trend 0.03. The corresponding figures for injurious falls were: 1.0, 1.17 (0.88-1.56), 1.06 (0.79- 1.41), 1.13 (0.84-1.52), and 1.40 (1.03-1.90); p-trend 0.10. These associations did not vary over strata of age, protein, calcium or vitamin intake, diet quality, physical activity or alcohol consumption. No differences were found when solid and liquid sources of added sugars were examined separately. Conclusions: Intake of added sugars was associated with a higher risk of falling in older people. This adds to the evidence to support interventions to reduce added sugar intake.
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