转化生长因子-?1、不孕不育

Suaad Hilal
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引用次数: 0

摘要

摘要:男性不育是影响10-15%育龄男性的一个问题。本研究旨在检测转化生长因子-?2022年9月至2023年3月期间,Al-Nasiriya教育医院/不孕症科/伊拉克Thi-Qar省门诊男性不孕症患者1 (TGF- 1)细胞因子的变化。采用夹心elisa法对88例男性不育症患者(76例,对照组12例)进行血清检测。不孕症患者分为原发性和继发性不孕症,分别为66例(86.84%)和10例(13.016%)(P < 0.01)。所有不孕症患者血清中TGF-?1为(0.734±0.45 pg/ml),对照组为(0.670±0.393 pg/ml)。本研究两组间该细胞因子比较差异无统计学意义(P>0.05)。该研究结果可能揭示TGF-?1作为男性不育症的血清学工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Transforming Growth Factor-?1 and infertility
Abstract: Male infertility is a problem that affects 10–15% of men in reproductive age. The present study aimed to detect the role Transforming Growth Factor-?1 (TGF-?1) cytokine in infertility outpatients’ males at Al-Nasiriya Educational Hospital / Infertility Unit / Thi-Qar Governorate Iraq, during the period from September 2022 to March 2023. Serum samples from 88 (76 infertility males and 12 control) were collected and assayed by Sandwich-ELISA technique. Infertility patients were distributed to Primary and secondary infertility type with a 66(86.84%) and 10(13.016%) patient, respectively (P?0.01). All infertility patients showed an elevated mean sera levels of TGF-?1 with (0.734±0.45 pg/ml), as compared with the controls (0.670± 0.393 pg/ml). No statistical differences were appeared between the two groups included in the present study regarding this cytokine (P>0.05). The study results may shed light the role of TGF-?1 as a serological tool in male infertility. 
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