{"title":"阿托伐他汀与辛伐他汀在大鼠体内的抗高脂血症活性比较","authors":"G. Rajyalakshmi, A. N. Reddy, V. V. Rajesham","doi":"10.5580/203b","DOIUrl":null,"url":null,"abstract":"The present study was aimed at comparing the pharmacodynamics of simvastatin (S) with atorvastatin in hyperlipidemic rats. The standard cholesterol diet was used to induce hyperlipidemia in Wister rats. The blood samples were collected from simvastatin and atorvastatin treated rats and analyzed for pharmacodynamics (lipid profiles) of using reported methods. Simvastatin produced a more significant change in lipid profiles than atorvastatin.","PeriodicalId":22523,"journal":{"name":"The Internet Journal of Pharmacology","volume":"83 2 Suppl 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"10","resultStr":"{\"title\":\"A Comparative Antihyperlipidemic Activity Of Atorvastatin With Simvastatin In Rats\",\"authors\":\"G. Rajyalakshmi, A. N. Reddy, V. V. Rajesham\",\"doi\":\"10.5580/203b\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The present study was aimed at comparing the pharmacodynamics of simvastatin (S) with atorvastatin in hyperlipidemic rats. The standard cholesterol diet was used to induce hyperlipidemia in Wister rats. The blood samples were collected from simvastatin and atorvastatin treated rats and analyzed for pharmacodynamics (lipid profiles) of using reported methods. Simvastatin produced a more significant change in lipid profiles than atorvastatin.\",\"PeriodicalId\":22523,\"journal\":{\"name\":\"The Internet Journal of Pharmacology\",\"volume\":\"83 2 Suppl 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2008-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"10\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Internet Journal of Pharmacology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5580/203b\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Internet Journal of Pharmacology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5580/203b","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A Comparative Antihyperlipidemic Activity Of Atorvastatin With Simvastatin In Rats
The present study was aimed at comparing the pharmacodynamics of simvastatin (S) with atorvastatin in hyperlipidemic rats. The standard cholesterol diet was used to induce hyperlipidemia in Wister rats. The blood samples were collected from simvastatin and atorvastatin treated rats and analyzed for pharmacodynamics (lipid profiles) of using reported methods. Simvastatin produced a more significant change in lipid profiles than atorvastatin.
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