腹部胃肠道间质瘤:12例患者的研究

I. Wani, I. Muzafar, I. Bakshi, N. Khan, M. Thoker
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摘要

胃肠道间质瘤是一种罕见的胃肠道间质肿瘤。胃和小肠是这些肿瘤最容易发生的部位。在临床基础上对此类肿瘤进行术前诊断是困难的,只有对标本进行详细的组织病理学检查才能揭示其真实性质。本研究的目的是在普通外科病房检查腹部胃肠道间质瘤。材料与方法对诊断为腹部胃肠道间质瘤的患者进行回顾性病例回顾研究。记录了这些患者的临床表现、手术表现和随访情况。在随访期间记录复发和新肿瘤的发展情况。结果对12例腹部胃肠道间质瘤进行了检查。男9例,女3例。8例诊断为腹部肿块,1例诊断为腹膜炎,1例诊断为上消化道出血,1例诊断为直肠出血,1例诊断为肠梗阻。所有患者均行剖腹探查,术后给予伊马替尼治疗。结论腹部胃肠道间质瘤是一种罕见的恶性肿瘤。这些肿瘤有不同的临床表现,腹部肿块是常见的症状。手术切除阴性切缘是治疗胃肠道间质瘤的首选方式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Abdominal gastrointestinal stromal tumours: a study of twelve patients
Introduction Gastrointestinal stromal tumour is a rare mesenchymal tumour of the gastrointestinal tract. The stomach and small intestine are the favoured sites for these tumours. Pre-operative diagnosis is difficult on clinical basis for such tumours and only a detailed histopathological examination of specimen reveals its true nature. The aim of this research study was to examine abdominal gastrointestinal stromal tumour in a general surgery ward. Materials and methods A retrospective case review study of patients, who had a diagnosis of the abdominal gastrointestinal stromal tumour, was performed. Clinical presentation, operative findings and a follow-up was recorded for these patients. Recurrence and development of a new tumour was recorded during the follow-up. Results Twelve patients, who had an abdominal gastrointestinal stromal tumour, were examined. There were nine male patients and three female patients. Eight patients were diagnosed with an abdominal mass, one patient had peritonitis, one patient had an upper gastrointestinal bleeding, one patient had rectal bleeding and one patient was diagnosed with an intestinal obstruction. All the patients had exploratory laparotomy and postoperative imatinib was given to them. Conclusion Gastrointestinal stromal tumour in the abdomen is a rare cancer. These tumours have variable clinical behaviour, with abdominal mass being the common symptom. Surgical resection with negative margin is the preferred modality of treatment for gastrointestinal stromal tumour.
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