钌-三联吡啶衍生物作为电化学发光生物传感器的神圣配合物

Chikkili Venkateswara Raju, Mathavan Sornambigai, Shanmugam Senthil Kumar
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引用次数: 1

摘要

在电化学发光(ECL)研究中,自1972年以来,三(联吡啶)钌(II)氯化(Ru(bpy) 32 +)及其衍生物被用作初级发光基团。Ru(bpy) 32 +在水和非水介质中的灵活溶解度以及化学、光学和理想的电化学行为等显著的内在特性促使研究人员使用Ru(bpy) 32 +及其衍生物作为现代分析科学中高活性的ECL探针。Ru(bpy) 32 +基ECL平台的新型表面修饰在生物分子的选择性和敏感性检测、DNA分析、免疫检测以及生物细胞和组织中重要分子的成像方面具有重要意义。本章讨论并重点介绍了基于Ru(bpy) 32 +的ECL性质的反应机理及其应用方面最重要的工作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ruthenium-Tris-Bipyridine Derivatives as a Divine Complex for Electrochemiluminescence Based Biosensor Applications
In electrochemiluminescence (ECL) studies, Tris (bipyridine)ruthenium(II) chloride (Ru(bpy)3 2+) and its derivatives have been used as primary luminophores since 1972. The flexible solubility in both aqueous and non-aqueous medium and the remarkable intrinsic properties like chemical, optical and desirable electrochemical behavior drives the researcher to use Ru(bpy)3 2+ and its derivatives as highly active ECL probes in modern analytical science. Novel surface modification of Ru(bpy)3 2+ based ECL platforms are highly useful in the selective and sensitive detection of biomolecules, DNA analysis, immunoassays detection, and imaging of the biologically important molecules in cells and tissue of living organisms. This chapter discusses and highlights the most significant works in Ru(bpy)3 2+ based ECL properties of reaction mechanisms and their applications.
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