Prostate tumour originating from interstitial cells of Cajal: a case presentation and review of the literature

We present a case of an extremely rare, atypical prostate tumour, diagnosed in a 57-year-old man, who reported pain in the pelvic area, problems with defe cation and lower urinary tract symp toms (LUTS). A giant prostate tumour was diagnosed in computed tomogra phy. The histopathological examination findings from core needle biopsy of mul tiple sites were not unequivocal. The patient underwent pelvic exenterative surgery. Also Bricker ileal conduit uri nary diversion and sigmoidostomy were performed. Histopathological examina tion of the surgical specimen revealed a gastrointestinal stromal tumour orig inating from the prostate and infiltrat ing the urinary bladder and the rectum. The patient was qualified for systemic adjuvant chemotherapy, but he did not give his consent to that treatment. Clin ical evaluation at 6 months following the surgery revealed major improve ment in the patient’s health status, but the patient still rejects adjuvant treat ment. The paper also presents an overview of the literature on gastrointestinal stro mal tumour (GIST) of the prostate.