中重度COVID-19肺炎患者临床特征及影像学随访研究

Vijayakumar, Apoorva Ravi, V. Pranavi
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引用次数: 0

摘要

2019冠状病毒病大流行是世界经历的现代启示录,到2022年死亡人数将达到6010万人。虽然许多病人从这种疾病中恢复过来,但大部分人口因感染的后遗症而致残。其中一个并发症是肺纤维化的发展,特别是在几项研究中报道的中至重度COVID-19感染后康复的患者中。尽管在早期充分使用抗病毒药物、抗生素和类固醇,但某些患者不可避免地会发生肺纤维化。在这里,我们报告了4例从COVID-19感染中恢复但在疾病过程中出现肺纤维化的病例。随访6个月,同时使用抗纤维化药物治疗,并评估临床和放射学的改善情况。在随访的CT扫描中,4名患者中有3名表现出好转,但1名患者的纤维化随着间质性肺病的进展而恶化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical profile and radiological pattern in follow-up study of patients treated for moderate-to-severe COVID-19 pneumonia
The COVID-19 pandemic is the modern-day apocalypse that the world has experienced, with a death toll of 60.1 lakh by 2022. Although many patients recovered from the disease, a major part of the population has been crippled with the sequelae that occurred with the infection. One such complication is the development of pulmonary fibrosis, especially among those who recovered from moderate-to-severe COVID-19 infection that has been reported in several studies. Albeit adequate and early usage of antivirals, antibiotics, and steroids, and the development of lung fibrosis was inevitable in certain patients. Here, we report four cases, who recovered from COVID-19 infection but developed pulmonary fibrosis along the course of illness. They were followed for 6 months, along with treatment with antifibrotics, and were assessed for improvement, both clinically and radiologically. While three among the four patients showed resolution in their follow-up CT scans, one patient's fibrosis worsened with progression to interstitial lung disease.
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