自我控制对妊娠期糖尿病病程及结局的影响

I. Barykina, E. Popova, A. Salasyuk, V. Lutova, A. A. Vachugova
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引用次数: 0

摘要

妊娠期糖尿病的特点是在分娩时发生巨大胎儿和产科并发症的风险增加,以及妊娠后母亲患2型糖尿病的风险增加。妊娠期及时诊断和治疗高血糖可减少不良妊娠结局。怀孕期间严格控制血糖的第一步是自我监测血糖。目的:评价卫星快速血糖仪对妊娠期糖尿病(GDM)患者常规血糖控制的临床应用效果。材料和方法。这项为期96周的前瞻性观察性非干预性研究纳入了150例GDM患者。在确诊为GDM的女性中,使用卫星快速血糖仪测量血糖。在每次就诊时,根据血糖结果(来自自我监测日记的数据)确定进一步治疗GDM的策略。直到怀孕第34周,每两周以医疗预约和电话联系的形式咨询内分泌学家1次。怀孕34周后,以每周一次的频率咨询内分泌学家。分娩后6-12周,进行口服葡萄糖耐量试验并咨询内分泌科医生,以评估碳水化合物代谢紊乱的程度。结果。参与研究的138例(92%)患者以分娩结束,12例(8%)患者提前退出研究。每天自我监测血糖0 ~ 1次的患者自然流产较多,每天自我监测3 ~ 4次的患者独立分娩较多,且血糖指标较为稳定。138名患者中有9名生育了体重在4000克以上的孩子。其余孩子出生时的体重都不超过3500克。结论。良好控制的妊娠期糖尿病病程,充分的自我监测和对妇女的动态观察,可以在普遍接受的条件下进行分娩,而不会恶化其结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Influence of Self-Control on the Course and Outcomes of Gestational Diabetes Mellitus
Gestational diabetes mellitus is characterized by an increased risk of fetal macrosomia and obstetric complications during childbirth, as well as the development of type 2 diabetes in the mother after pregnancy. Timely diagnosis and treatment of hyperglycemia during pregnancy reduces adverse pregnancy outcomes. The first step towards tight glucose control during pregnancy is self-monitoring of glycemia. Aim: to evaluate the effectiveness of regular glycemic control using a Satellite express glucometer calibrated on capillary whole blood in patients with gestational diabetes mellitus (GDM) in outpatient practice. Material and methods. The 96-week prospective observational non-interventional study included 150 patients with GDM. In women with confirmed GDM, blood glucose was measured using a satellite express glucometer. At each visit, further tactics for the treatment of GDM were determined based on the results of glycemia (data from the self-monitoring diary). Until the 34th week of pregnancy, an endocrinologist was consulted with a frequency of 1 time in 2 weeks in the form of a medical appointment and telephone contact. After 34 weeks of pregnancy, consultation of an endocrinologist with a frequency of 1 time per week. 6–12 weeks after delivery, an oral glucose tolerance test and consultation with an endocrinologist were performed to assess the degree of carbohydrate metabolism disorder. Results. The participation of 138 (92%) patients in the study ended in childbirth, 12 (8%) patients dropped out of the study ahead of schedule. Spontaneous abortions were noted in patients who performed self-monitoring of glycemia 0–1 times a day, independent births were more often observed in patients who performed self-monitoring 3–4 times a day, and these patients also had more stable glycemic indices. 9 patients out of 138 gave birth to children weighing 4000 g or more. The weight of the rest of the children at birth did not exceed 3500 g. Conclusion. A well-controlled course of GDM, adequate self-monitoring and dynamic observation of women allows delivery to be carried out within the generally accepted terms without worsening its outcomes.
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