毛霉病:涉及COVID-19患者的严重灾难

Neha Dangi, Himanshu Mehendiratta, Shikha Sharma
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引用次数: 0

摘要

由“严重急性呼吸综合征冠状病毒-2”(SARS-CoV-2)引发的全球大流行COVID-19,对印度造成了巨大影响。随着一种名为毛霉病的罕见真菌的出现,第二波COVID-19在初始阶段之后对印度人口产生了重大影响。毛霉菌病也被称为“黑菌”,因为感染的皮肤组织坏死,导致皮肤变黑。它是由粘菌引起的,粘菌是接合菌目和粘菌纲的成员。COVID-19对各种合并症的影响,如糖尿病、心脏病和免疫功能低下状态,从轻微到严重到危及生命。毛霉菌病霉菌更容易影响高血糖、酮症酸中毒、实体器官或骨髓移植、肝硬化或中性粒细胞减少的患者。为了消除毛霉病,必须解决四个主要变量:早期诊断,根除易感因素,及时通过手术切除所有病变组织进行抗真菌治疗,以及辅助治疗。现就黑木耳的临床病因、症状、诊断及治疗作一综述。该研究得出结论,使用免疫抑制药物来对抗Covid-19也会增加感染毛霉菌病的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mucormycosis: A serious catastrophe involving COVID-19 patients
With the global pandemic, COVID-19, spurred on by the "Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2)," India has been greatly impacted. With a rare fungus known as Mucormycosis, the second wave of COVID-19 significantly impacted the Indian population after the initial phase. Mucormycosis is also known as "black fungus" because of the necrosis of infected skin tissue, which causes it to become black. It is caused by Mucoromycetes, members of the Zygomycetes order and the Mucorales class. COVID-19's effects on various comorbid ailments, such as diabetes, heart problems, and immune-compromised states, range from mild to severe to life-threatening. Mucormycosis moulds are more likely to affect patients who have hyperglycemia, ketoacidosis, solid organ or bone marrow transplantation, liver cirrhosis, or neutropenia. To eliminate Mucormycosis, four primary variables must be addressed: early diagnosis, eradication of predisposing factors, prompt antifungal treatment with surgical removal of all diseased tissues, and adjuvant therapies. Here, the present review discusses the clinical aetiology, symptoms, diagnosis, and therapy for black fungus. The study leads to the conclusion that the use of immunosuppressant medication to combat Covid-19 also elevates the possibility of being infected with mucormycotic.
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