COVID-19的代谢风险和预后:饮食模式重要吗?

Hande Bakırhan, Fatmanur Özyürek Arpa, Halime Uğur, Merve Pehlivan, Neda Saleki, T. Çelik
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摘要

目的本研究旨在确定两组受试者(感染和未感染COVID-19)的饮食模式,并评估结果与COVID-19预后和代谢危险参数的关系。设计/方法/方法本研究包括100名年龄在19-65岁之间的个体。病历、生化、血液学和炎症指标数据从档案中检索。采用面对面访谈的方式对受试者进行24小时进食记录和进食频率问卷调查,并对受试者的饮食模式进行评估。结果新冠肺炎患者的臀围、腰臀比、体脂率显著增高(p < 0.05),肌肉质量率显著降低(p < 0.05)。两组的地中海饮食依从性筛查(MEDAS)、饮食方法停止高血压(DASH)和健康饮食ındex-2015 (HEI-2015)评分均较低。DASH评分与肌肉质量百分比呈线性相关(p = 0.046),与体脂率呈显著负相关(p = 0.006)。HEI-2015评分与体重、体质指数、腰围、臀围、颈围呈显著负相关(p < 0.05)。MEDAS、DASH和HEI-2015评分每增加一个单位,c反应蛋白水平就会不同程度地降低。肌钙蛋白- 1与水果摄入量(p = 0.044)、地中海饮食的组成部分以及HEI-2015总分呈显著负相关(p = 0.032)。研究的局限性/启示本研究的局限性包括样本量小和缺乏饮食干预。另一个限制是使用食品召回法来评估饮食模式。通过这种方式,评估是基于参与者的记忆和陈述进行的。实际意义遵循健康的饮食模式可以帮助降低COVİD-19疾病的代谢风险。尽管存在这些局限性,但这项研究还是有价值的,因为据作者所知,这是第一个证明饮食模式与COVID-19疾病预后和代谢风险之间存在关联的研究。这项研究表明,COVID-19过程中的饮食模式可能与几种代谢风险和炎症生物标志物有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Metabolic risks and prognosis of COVID-19: are dietary patterns important?
Purpose This study aims to identify the dietary patterns of two groups of subjects (with and without COVID-19), and to assess the relationship of findings with the prognosis of COVID-19 and metabolic risk parameters. Design/methodology/approach This study included 100 individuals in the age range of 19–65 years. The medical history, and data on biochemical, hematological and inflammatory indicators were retrieved from the files. A questionnaire for the 24-h food record and the food intake frequency was administered in face-to-face interviews, and dietary patterns of subjects were assessed. Findings In individuals with COVID-19, the hip circumference, the waist-hip ratio and the body fat percentage were significantly higher (p < 0.05), and the muscle mass percentage was significantly lower (p < 0.05). Mediterranean diet adherence screener (MEDAS), dietary approaches to stop hypertension (DASH) and healthy eating ındex-2015 (HEI-2015) scores were low in the two groups. A linear correlation of DASH scores was found with the muscle mass percentage (p = 0.046) and a significant inverse correlation of with the body fat percentage (p = 0.006). HEI-2015 scores were significantly and negatively correlated with body weight, body mass index, waist circumference, hip circumference and neck circumference (p < 0.05). Every one-unit increase in MEDAS, DASH and HEI-2015 scores caused reductions in C-reactive protein levels at different magnitudes. Troponin-I was significantly and negatively correlated with fruit intake (p = 0.044), a component of a Mediterranean diet and with HEI-2015 total scores (p = 0.032). Research limitations/implications The limitation of this study includes the small sample size and the lack of dietary interventions. Another limitation is the use of the food recall method for the assessment of dietary patterns. This way assessments were performed based on participants’ memory and statements. Practical implications Following a healthy diet pattern can help reduce the metabolic risks of COVİD-19 disease. Originality/value Despite these limitations, this study is valuable because, to the best of the authors’ knowledge, it is the first study demonstrating the association of dietary patterns with disease prognosis and metabolic risks concerning COVID-19. This study suggests that dietary patterns during the COVID-19 process may be associated with several metabolic risks and inflammatory biomarkers.
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