咪喹莫特预处理是否能优化308 nm准分子激光(UVB)治疗银屑病患者?

Photodermatology Pub Date : 2017-07-01 DOI:10.1111/phpp.12299

Joselin D Tacastacas, P. Oyetakin‐White, D. Soler, A. Young, S. Groft, K. Honda, K. Cooper, T. McCormick

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引用次数: 6

摘要

牛皮癣仍然是一种使人衰弱的皮肤病，影响美国人口的1-3%。尽管目前几种生物疗法的有效性已经将这种病理描述为IL - 23、TNF - a和Th17介导的疾病，但侵入性较小的方法仍在使用中，需要改进。其中之一是使用窄带- UVB (NB - UVB)治疗，专门消耗表皮内CD3+、CD4+和CD8+细胞，以清除银屑病斑块。

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Does imiquimod pretreatment optimize 308‐nm excimer laser (UVB) therapy in psoriasis patients?

Psoriasis continues to be a debilitating skin disease affecting 1–3% of the United States population. Although the effectiveness of several current biologic therapies have described this pathology as a IL‐23, TNF‐a and Th17‐mediated disease, less invasive approaches are still in use and in need of refinement. One of these is the usage of narrow band‐UVB (NB‐UVB) therapy to deplete specifically intra‐epidermal CD3+, CD4+ and CD8+ cells to clear psoriatic plaques.

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Photodermatology

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