Chun-lei Zhou, Xiangfang Yang, Zhihui Xie, D. Miao, Yong Sun, Bin Shi
{"title":"飞行人员冠状动脉狭窄危险因素调查","authors":"Chun-lei Zhou, Xiangfang Yang, Zhihui Xie, D. Miao, Yong Sun, Bin Shi","doi":"10.3760/CMA.J.ISSN.1007-6239.2018.03-04.007","DOIUrl":null,"url":null,"abstract":"Objective \nTo investigate the main risk factors induced to coronary artery stenosis in order to provide evidence for prevention of coronary heart disease in flying personnel. \n \n \nMethods \nBy analyzing the computed tomography angiography (CTA), 44 flying personnel clinically suspected as coronary heart disease were divided into coronary artery stenosis group and normal coronary artery group. The comparisons on age, flying aircraft type, flying duties, body mass index (BMI), flying hours, night flying hours, blood lipid level, serum glucose level, histories of hypertension and smoking were conducted between two groups. The Logistic multivariate regression analysis was used for determining risk factors. \n \n \nResults \nThe CTA results indicated 25 cases (56.82%) of coronary artery stenosis and 19 normal cases. The univariate analysis showed the statistical differences on age, flight hours, night flight hours, and the incidences of hypercholesterolemia, hyper low-density lipoprotein cholesterolemia, Hypo high-density lipoprotein cholesterolemia and hypertriglyceridemia between coronary artery stenosis group and coronary artery normal group (χ2=4.429-14.329, P<0.05). The Logistic multivariate regression analysis showed that hyper low-density lipoprotein cholesterolemia (OR=7.026, 95%CI: 1.831-26.959, P<0.05) and night flight hours (OR=4.461, 95%CI: 1.694-11.746, P<0.05) were the independent risk factors of coronary artery stenosis. \n \n \nConclusions \nHyper low-density lipoprotein cholesterolemia and night flying hours are the independent risk factors of coronary artery stenosis in pilots. These hint that the change of circadian rhythms would be an important factor to induce coronary artery stenosis besides the common risk factors. \n \n \nKey words: \nCoronary artery stenosis; Circadian rhythm; Risk factors; Flying personnel","PeriodicalId":9904,"journal":{"name":"Chinese Journal of Aerospace Medicine","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2018-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Investigation of risk factors of coronary artery stenosis in flying personnel\",\"authors\":\"Chun-lei Zhou, Xiangfang Yang, Zhihui Xie, D. Miao, Yong Sun, Bin Shi\",\"doi\":\"10.3760/CMA.J.ISSN.1007-6239.2018.03-04.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective \\nTo investigate the main risk factors induced to coronary artery stenosis in order to provide evidence for prevention of coronary heart disease in flying personnel. \\n \\n \\nMethods \\nBy analyzing the computed tomography angiography (CTA), 44 flying personnel clinically suspected as coronary heart disease were divided into coronary artery stenosis group and normal coronary artery group. The comparisons on age, flying aircraft type, flying duties, body mass index (BMI), flying hours, night flying hours, blood lipid level, serum glucose level, histories of hypertension and smoking were conducted between two groups. The Logistic multivariate regression analysis was used for determining risk factors. \\n \\n \\nResults \\nThe CTA results indicated 25 cases (56.82%) of coronary artery stenosis and 19 normal cases. The univariate analysis showed the statistical differences on age, flight hours, night flight hours, and the incidences of hypercholesterolemia, hyper low-density lipoprotein cholesterolemia, Hypo high-density lipoprotein cholesterolemia and hypertriglyceridemia between coronary artery stenosis group and coronary artery normal group (χ2=4.429-14.329, P<0.05). The Logistic multivariate regression analysis showed that hyper low-density lipoprotein cholesterolemia (OR=7.026, 95%CI: 1.831-26.959, P<0.05) and night flight hours (OR=4.461, 95%CI: 1.694-11.746, P<0.05) were the independent risk factors of coronary artery stenosis. \\n \\n \\nConclusions \\nHyper low-density lipoprotein cholesterolemia and night flying hours are the independent risk factors of coronary artery stenosis in pilots. These hint that the change of circadian rhythms would be an important factor to induce coronary artery stenosis besides the common risk factors. \\n \\n \\nKey words: \\nCoronary artery stenosis; Circadian rhythm; Risk factors; Flying personnel\",\"PeriodicalId\":9904,\"journal\":{\"name\":\"Chinese Journal of Aerospace Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-12-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chinese Journal of Aerospace Medicine\",\"FirstCategoryId\":\"1087\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.1007-6239.2018.03-04.007\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chinese Journal of Aerospace Medicine","FirstCategoryId":"1087","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1007-6239.2018.03-04.007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Investigation of risk factors of coronary artery stenosis in flying personnel
Objective
To investigate the main risk factors induced to coronary artery stenosis in order to provide evidence for prevention of coronary heart disease in flying personnel.
Methods
By analyzing the computed tomography angiography (CTA), 44 flying personnel clinically suspected as coronary heart disease were divided into coronary artery stenosis group and normal coronary artery group. The comparisons on age, flying aircraft type, flying duties, body mass index (BMI), flying hours, night flying hours, blood lipid level, serum glucose level, histories of hypertension and smoking were conducted between two groups. The Logistic multivariate regression analysis was used for determining risk factors.
Results
The CTA results indicated 25 cases (56.82%) of coronary artery stenosis and 19 normal cases. The univariate analysis showed the statistical differences on age, flight hours, night flight hours, and the incidences of hypercholesterolemia, hyper low-density lipoprotein cholesterolemia, Hypo high-density lipoprotein cholesterolemia and hypertriglyceridemia between coronary artery stenosis group and coronary artery normal group (χ2=4.429-14.329, P<0.05). The Logistic multivariate regression analysis showed that hyper low-density lipoprotein cholesterolemia (OR=7.026, 95%CI: 1.831-26.959, P<0.05) and night flight hours (OR=4.461, 95%CI: 1.694-11.746, P<0.05) were the independent risk factors of coronary artery stenosis.
Conclusions
Hyper low-density lipoprotein cholesterolemia and night flying hours are the independent risk factors of coronary artery stenosis in pilots. These hint that the change of circadian rhythms would be an important factor to induce coronary artery stenosis besides the common risk factors.
Key words:
Coronary artery stenosis; Circadian rhythm; Risk factors; Flying personnel