{"title":"ACTH > 2000 pg/ml;是免疫分析干扰还是其他问题?","authors":"Vivek Pant, S. Pradhan","doi":"10.3126/jpn.v13i1.54455","DOIUrl":null,"url":null,"abstract":"Starting rifampicin in patients with Addison’s disease or adrenal tuberculosis may precipitate an adrenal crisis as a result of the induction of CYP 3A4 which in turn leads to increased breakdown of cortisol. We report this rare phenomenon to increase awareness among healthcare professionals. ","PeriodicalId":31517,"journal":{"name":"Journal of Pathology of Nepal","volume":"68 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ACTH more than 2000 pg/ml; is it immunoassay interference or another matter?\",\"authors\":\"Vivek Pant, S. Pradhan\",\"doi\":\"10.3126/jpn.v13i1.54455\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Starting rifampicin in patients with Addison’s disease or adrenal tuberculosis may precipitate an adrenal crisis as a result of the induction of CYP 3A4 which in turn leads to increased breakdown of cortisol. We report this rare phenomenon to increase awareness among healthcare professionals. \",\"PeriodicalId\":31517,\"journal\":{\"name\":\"Journal of Pathology of Nepal\",\"volume\":\"68 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pathology of Nepal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3126/jpn.v13i1.54455\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pathology of Nepal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3126/jpn.v13i1.54455","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
ACTH more than 2000 pg/ml; is it immunoassay interference or another matter?
Starting rifampicin in patients with Addison’s disease or adrenal tuberculosis may precipitate an adrenal crisis as a result of the induction of CYP 3A4 which in turn leads to increased breakdown of cortisol. We report this rare phenomenon to increase awareness among healthcare professionals.
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