新诊断慢性淋巴细胞白血病(CLL)患者的COVID-19: 1例报告

Alireza Gandomi-Mohammadabadi, Farshad Divsalar, S. Taram, Zahra Kateb, F. Montazer, Yasaman Farbod, Seyedamir Tabibzadeh Dezfooli, A. Abbasi, M. Abbasi
{"title":"新诊断慢性淋巴细胞白血病(CLL)患者的COVID-19: 1例报告","authors":"Alireza Gandomi-Mohammadabadi, Farshad Divsalar, S. Taram, Zahra Kateb, F. Montazer, Yasaman Farbod, Seyedamir Tabibzadeh Dezfooli, A. Abbasi, M. Abbasi","doi":"10.52547/rabms.7.1.26","DOIUrl":null,"url":null,"abstract":"Chronic lymphocytic leukemia (CLL) is one of the most common hematologic neoplasms leading to immunosuppression. It is characterized by absolute lymphocytosis with clonality of mature B cells. Therefore, they are vulnerable to various infections especially COVID-19. Little is known about the COVID-19 infection when it unmasks CLL. We reported a 90-year-old man who presented with signs and symptoms of anorexia, weakness, and loss of consciousness, and lymphocytosis which in further workup COVID-19 confirmed with real-time PCR. Due to lymphocytosis, peripheral blood smear (PBS) and flow cytometry were performed and CLL was diagnosed. His lymphocyte count increased to 1.5-fold during hospitalization. The patient recovered after 11 days as the symptoms were alleviated. in lymphocytes may indicate other conditions. In these cases, secondary causes of lymphocytosis, such as malignancy or other infections, should be considered","PeriodicalId":16970,"journal":{"name":"Journal of Research in Applied and Basic Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"COVID-19 in a Patient with Newly Diagnosed Chronic Lymphocytic Leukemia (CLL): A Case Report\",\"authors\":\"Alireza Gandomi-Mohammadabadi, Farshad Divsalar, S. Taram, Zahra Kateb, F. Montazer, Yasaman Farbod, Seyedamir Tabibzadeh Dezfooli, A. Abbasi, M. Abbasi\",\"doi\":\"10.52547/rabms.7.1.26\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Chronic lymphocytic leukemia (CLL) is one of the most common hematologic neoplasms leading to immunosuppression. It is characterized by absolute lymphocytosis with clonality of mature B cells. Therefore, they are vulnerable to various infections especially COVID-19. Little is known about the COVID-19 infection when it unmasks CLL. We reported a 90-year-old man who presented with signs and symptoms of anorexia, weakness, and loss of consciousness, and lymphocytosis which in further workup COVID-19 confirmed with real-time PCR. Due to lymphocytosis, peripheral blood smear (PBS) and flow cytometry were performed and CLL was diagnosed. His lymphocyte count increased to 1.5-fold during hospitalization. The patient recovered after 11 days as the symptoms were alleviated. in lymphocytes may indicate other conditions. In these cases, secondary causes of lymphocytosis, such as malignancy or other infections, should be considered\",\"PeriodicalId\":16970,\"journal\":{\"name\":\"Journal of Research in Applied and Basic Medical Sciences\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Research in Applied and Basic Medical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52547/rabms.7.1.26\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Research in Applied and Basic Medical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52547/rabms.7.1.26","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

慢性淋巴细胞白血病(CLL)是最常见的导致免疫抑制的血液肿瘤之一。它的特点是成熟B细胞的绝对淋巴细胞增多和克隆性。因此,他们很容易受到各种感染,特别是COVID-19。当COVID-19感染揭开CLL的面纱时,人们对它知之甚少。我们报告了一名90岁的男性,他表现出厌食、虚弱、意识丧失和淋巴细胞增多的体征和症状,并在进一步的COVID-19检查中通过实时PCR证实。由于淋巴细胞增多,行外周血涂片(PBS)和流式细胞术,诊断为CLL。住院期间淋巴细胞计数增加1.5倍。11天后,患者症状减轻,康复。在淋巴细胞中可能提示其他情况。在这些病例中,应考虑淋巴细胞增多的继发原因,如恶性肿瘤或其他感染
本文章由计算机程序翻译,如有差异,请以英文原文为准。
COVID-19 in a Patient with Newly Diagnosed Chronic Lymphocytic Leukemia (CLL): A Case Report
Chronic lymphocytic leukemia (CLL) is one of the most common hematologic neoplasms leading to immunosuppression. It is characterized by absolute lymphocytosis with clonality of mature B cells. Therefore, they are vulnerable to various infections especially COVID-19. Little is known about the COVID-19 infection when it unmasks CLL. We reported a 90-year-old man who presented with signs and symptoms of anorexia, weakness, and loss of consciousness, and lymphocytosis which in further workup COVID-19 confirmed with real-time PCR. Due to lymphocytosis, peripheral blood smear (PBS) and flow cytometry were performed and CLL was diagnosed. His lymphocyte count increased to 1.5-fold during hospitalization. The patient recovered after 11 days as the symptoms were alleviated. in lymphocytes may indicate other conditions. In these cases, secondary causes of lymphocytosis, such as malignancy or other infections, should be considered
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信