三尖瓣反流压梯度诊断肺动脉高压的准确性研究

IF 0.2 Q4 PEDIATRICS
I. Murni, Emmanuel Mareffcita Siagian, N. Nurnaningsih, Nadya Arafuri
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引用次数: 0

摘要

背景:肺动脉高压在儿童中具有很高的发病率和死亡率。早期诊断和治疗可以改善肺动脉高压患儿的预后。心导管插入术是诊断肺动脉高压的金标准,是一种侵入性手术,并没有广泛应用。超声心动图可作为肺动脉高压的另一种诊断工具。目的探讨超声心动图三尖瓣反流压力梯度与心导管检查对儿童肺动脉高压的诊断价值。方法本诊断试验研究是对2018年1月至2020年12月在印度尼西亚日惹Dr. Sardjito医院接受心导管和超声心动图检查的无胎先天性心脏病儿童的病历数据进行的。对数据进行分析,获得敏感性、特异性、阳性和阴性预测值以及阳性和阴性似然比。结果共纳入98例无氰型先天性心脏病患儿。与心导管相比,三尖瓣反流压力梯度测定肺动脉压力的敏感性和特异性分别为64.4%和54.5%。阳性似然比为1.42。本研究的前测概率为88.7%,后测概率为91.7%。结论超声心动图测量三尖瓣反流压梯度诊断肺动脉高压的敏感性和特异性较差。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tricuspid regurgitation pressure gradient to diagnose pulmonary hypertension: a diagnostic accuracy study
Background Pulmonary hypertension carries significant morbidity and mortality in children. Early diagnosis and management may improve outcomes in children with pulmonary hypertension. Heart catheterization, a gold standard for diagnosing pulmonary hypertension, is an invasive procedure and not widely available. Echocardiography can be used as an alternative diagnostic tool for pulmonary hypertension. Objective To determine the diagnostic value of tricuspid regurgitation pressure gradient on echocardiography compared to heart catheterization to diagnose pulmonary hypertension in children. Methods This diagnostic test study was done with medical record data of children with acyanotic congenital heart disease who underwent cardiac catheterization and echocardiography procedures from January 2018 to December 2020 at Dr. Sardjito Hospital, Yogyakarta, Indonesia. Data were analyzed to obtain sensitivity, specificity, positive and negative predictive values, as well as positive and negative likelihood ratios. Results A total of 98 children with acyanotic congenital heart disease were included. The sensitivity and specificity of the tricuspid regurgitation pressure gradient to determine pulmonary artery pressure compared to heart catheterization were 64.4% and 54.5%, respectively. The positive likelihood ratio was 1.42. The pre-test and post-test probability of this study were 88.7% and 91.7%, respectively. Conclusion Tricuspid regurgitation pressure gradient measured using echocardiography has poor sensitivity and specificity to diagnose pulmonary hypertension.
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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
58
审稿时长
24 weeks
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