1Hz rTMS对慢性耳鸣有积极影响的证据是什么?

Natasha Phillips, Amr El Refaie
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引用次数: 2

摘要

目的:调查相关的长期研究,评估1Hz重复经颅磁刺激(rTMS)在慢性耳鸣患者中的应用,从而确定其作为一种可能的治疗选择的益处。研究设计:采用系统综述来总结研究问题。纳入包括使用1Hz rTMS进行的为期6个月的双盲随机假对照临床试验。搜索策略包括使用Pubmed、Cochrane Library、OVID Medline、CINAHL、Google Scholar、University of Bristol MetaLib和University of Bristol图书馆目录等数据库。结果:获得3项合适的研究,均符合纳入标准。结果表明,rTMS似乎具有持续6个月的有益心理和生理长期影响,尽管由于受试者之间的高度差异,尚未发现特定参与者特征与总体成功之间的相关性。结论:尽管rTMS对慢性耳鸣可能有益处,但仍需要进一步的研究来充分确定rTMS在6个月后的长期益处,并有可能将rTMS标准化为循证耳鸣管理工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
What is the evidence that 1Hz rTMS positively affects chronic tinnitus?
Objective: To investigate relevant long-term studies which assess the use of 1Hz repetitive transcranial magnetic stimulation (rTMS) in participants with chronic tinnitus and so determine its benefits as a possible treatment option. Study design: A systematic review was developed to conclude the research question. The inclusion involved double-blind randomized sham-controlled clinical trials conducted over six months using 1Hz rTMS. The search strategy included the use of databases such as Pubmed, Cochrane Library, OVID Medline, CINAHL, Google Scholar, University of Bristol MetaLib and the University of Bristol library catalogue. Results: Three suitable studies were obtained and fulfilled the inclusion criteria. The results indicated that rTMS appears to have a beneficial psychological and physiological long-term effect spanning six months, although a correlation between a particular participant trait and overall success has not been found due to high inter-subject variability. Conclusion: Despite the possible benefits of rTMS with chronic tinnitus, further research is still required to fully determine the long-term benefits of rTMS after six months and potentially standardize rTMS into an evidence-based tinnitus management tool.
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