在印度销售的一些商业品牌雷米普利片的比较体外评价

G. P D, S. K L, V. V, S. V, V. ., K. a, M. K, T. T
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引用次数: 0

摘要

印度药店中几种品牌的雷米普利片剂现在给医生带来了仿制药替代问题。本研究的目的是评估和比较印度各制药企业生产的不同品牌、不同商标的雷米普利,以减少健康风险,确保当地居民的安全。这些片剂的一般质量评估,如直径、厚度、硬度、重量变化、易碎性、崩解和溶出度测试,也根据公认的方案进行了,测试结果在可接受范围内。有效成分采用经批准的紫外分光光度法测定。这种类型的研究对于确定商业产品的理想性是有用的。关键词:雷米普利,体外评价,溶出度研究,崩解试验
本文章由计算机程序翻译,如有差异,请以英文原文为准。
COMPARATIVE IN VITRO EVALUATION OF SOME COMMERCIAL BRANDS OF RAMIPRIL TABLETS MARKETED IN INDIA
The availability of several brands of Ramipril tablets in Indian pharmacies now poses a generic replacement concern for doctors. The goal of this study was to evaluate and compare different brands of Ramipril manufactured by various Indian pharmaceutical businesses under various trade names in order to reduce health risks and ensure the safety of local residents. General quality assessments of these tablets, such as diameter, thickness, hardness, weight variation, friability, disintegration, and dissolution tests, were also carried out according to recognised protocols, with test results falling within the acceptable range. Active components were measured using an approved UV spectrophotometric technique. This type of research is useful for determining the idealness of commercial products. KEYWORDS: Ramipril, In vitro evaluation, Dissolution study, Disintegration test
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