{"title":"维生素C,老化皮肤,皮肤健康","authors":"P. Humbert, L. Louvrier, P. Saas, C. Viennet","doi":"10.5772/INTECHOPEN.81268","DOIUrl":null,"url":null,"abstract":"Vitamin C is an essential nutriment for humans. Vitamin C is known for its antioxidant potential. Vitamin C acts as a potent water-soluble antioxidant in biological fluids. Thus, topical vitamin C will not only reduce the risks of development of photoaging but also could reduce the risk of carcinogenesis. In addition to its antioxidant properties, vitamin C is essential for collagen synthesis. Vitamin C stimulates or restores several mechanisms which are either deficient or disturbed. Topical application of vitamin C partially restores the anatomical structure of the epidermal-dermal junction in young skin. A clinical trial confirmed for the first time that topical application of 5% vitamin C over a period of 6 months significantly improves the clinical appearance of photodamaged skin when compared to the vehicle alone. In inflammatory skin diseases, that is, atopic dermatitis and psoriasis, vitamin C levels into the dermis are reduced. Moreover, a randomized double-blind comparative study conducted in patients with Bateman purpura showed a significant improvement that vitamin C is probably one of the main topical anti-aging agents. In addition, the use of photo-protective sunscreen after UV irradiation prevents the decrease of acid ascorbic dermis concentration. Indeed, the ingestion of vitamin C has different benefits on skin such as wound healing, cutaneous aging, and prevention of skin cancer.","PeriodicalId":23668,"journal":{"name":"Vitamin C - an Update on Current Uses and Functions","volume":"18 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Vitamin C, Aged Skin, Skin Health\",\"authors\":\"P. Humbert, L. Louvrier, P. Saas, C. Viennet\",\"doi\":\"10.5772/INTECHOPEN.81268\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Vitamin C is an essential nutriment for humans. Vitamin C is known for its antioxidant potential. Vitamin C acts as a potent water-soluble antioxidant in biological fluids. Thus, topical vitamin C will not only reduce the risks of development of photoaging but also could reduce the risk of carcinogenesis. In addition to its antioxidant properties, vitamin C is essential for collagen synthesis. Vitamin C stimulates or restores several mechanisms which are either deficient or disturbed. Topical application of vitamin C partially restores the anatomical structure of the epidermal-dermal junction in young skin. A clinical trial confirmed for the first time that topical application of 5% vitamin C over a period of 6 months significantly improves the clinical appearance of photodamaged skin when compared to the vehicle alone. In inflammatory skin diseases, that is, atopic dermatitis and psoriasis, vitamin C levels into the dermis are reduced. Moreover, a randomized double-blind comparative study conducted in patients with Bateman purpura showed a significant improvement that vitamin C is probably one of the main topical anti-aging agents. In addition, the use of photo-protective sunscreen after UV irradiation prevents the decrease of acid ascorbic dermis concentration. Indeed, the ingestion of vitamin C has different benefits on skin such as wound healing, cutaneous aging, and prevention of skin cancer.\",\"PeriodicalId\":23668,\"journal\":{\"name\":\"Vitamin C - an Update on Current Uses and Functions\",\"volume\":\"18 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-11-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Vitamin C - an Update on Current Uses and Functions\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5772/INTECHOPEN.81268\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vitamin C - an Update on Current Uses and Functions","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5772/INTECHOPEN.81268","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Vitamin C is an essential nutriment for humans. Vitamin C is known for its antioxidant potential. Vitamin C acts as a potent water-soluble antioxidant in biological fluids. Thus, topical vitamin C will not only reduce the risks of development of photoaging but also could reduce the risk of carcinogenesis. In addition to its antioxidant properties, vitamin C is essential for collagen synthesis. Vitamin C stimulates or restores several mechanisms which are either deficient or disturbed. Topical application of vitamin C partially restores the anatomical structure of the epidermal-dermal junction in young skin. A clinical trial confirmed for the first time that topical application of 5% vitamin C over a period of 6 months significantly improves the clinical appearance of photodamaged skin when compared to the vehicle alone. In inflammatory skin diseases, that is, atopic dermatitis and psoriasis, vitamin C levels into the dermis are reduced. Moreover, a randomized double-blind comparative study conducted in patients with Bateman purpura showed a significant improvement that vitamin C is probably one of the main topical anti-aging agents. In addition, the use of photo-protective sunscreen after UV irradiation prevents the decrease of acid ascorbic dermis concentration. Indeed, the ingestion of vitamin C has different benefits on skin such as wound healing, cutaneous aging, and prevention of skin cancer.