冠状动脉成形术患者的处方模式及危险因素评估

N. Solanki, Nisha R Patel, S. Desai, V. Patel
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摘要

背景:冠状动脉疾病是由心脏血管供应阻塞引起的。血管成形术是CAD患者治疗中常用的干预手段。此外,还向这些患者提供支持性和预防性治疗。本研究的目的是评估冠心病患者的相关危险因素和处方趋势。方法:对88例接受冠状动脉成形术的患者进行前瞻性研究。对患者进行CAD危险因素评估。以病例记录表记录患者用药史,分析处方趋势及合理性。采用prism软件对数据进行统计学分析。结果:本组冠心病患者以男性居多(80.68%),平均年龄59.19岁。大多数患者(39.77%)年龄在61 ~ 70岁之间。入院时最常见的相关疾病是高血压和糖尿病。在本研究中,BMI、压力、缺乏运动、高血压、糖尿病、CVD家族史是冠心病的危险因素,与危险因素和冠状动脉疾病有显著相关性。常用药物为抗血小板、抗生素、降压药、抗溃疡药、降血脂药、降糖药(p<0.05)。19.31%的病例存在药物相互作用,其中重度2例。用依维莫司、西罗莫司包衣的支架也被开处方。结论:心血管病史、高血压、糖尿病是冠心病的主要危险因素。处方趋势存在一定程度的不合理性。适当的病人咨询和护理可以帮助预防冠心病和减轻健康负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Coronary artery disease prescribing pattern and risk factor assessment in the patients undergoing angioplasty
Background: Coronary artery disease is caused by an obstruction in vascular supply to the heart. Angioplasty is a frequently used intervention for the management of CAD patients. Supportive and preventive therapies are additionally provided to these patients. Objective of current study was to assess the associated risk factors as well as prescribing trends in CAD patients. Methods: A prospective study was conducted in 88 patients undergoing coronary angioplasty. Patients were assessed for risk factors of CAD. Medication history of patients was recorded in case record form for analysis of prescribing trend and its rationality. Data were statistically analyzed using prism software. Results: In present study most of the CAD patients were male (80.68%) and mean age of patient was 59.19 years. Majority of patients (39.77%) were in age range of 61-70 years. Most common associated conditions at admission were hypertension and diabetes. In this study, BMI, stress, lack of exercise, hypertension, diabetes, family history of CVD were risk factors of CAD and significant correlation observed with risk factors and coronary artery disease. (p<0.05) Frequently prescribed drugs were antiplatelet, antibiotics, antihypertensive, antiulcer, antihyperlipidemic, antidiabetic agents. In 19.31% cases, drug interaction was detected out of which two cases recorded severe. Medical stents coated with everolimus, sirolimus were also prescribed. Conclusions: It was concluded that history of cardiovascular disease, hypertension, diabetes are major risk factors of CAD. Certain level of irrationality in the prescribing trend was observed. Proper patient counselling and care can help in preventing CAD and reduces health burden.
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