靶向药物开发系统(TDDS)研究进展综述

Dhananjay D. Chaudhari, Satish D. Mali, Vaishnavi Chaudhari
{"title":"靶向药物开发系统(TDDS)研究进展综述","authors":"Dhananjay D. Chaudhari, Satish D. Mali, Vaishnavi Chaudhari","doi":"10.52711/2231-5659.2023.00008","DOIUrl":null,"url":null,"abstract":"Targeted drug delivery is an advanced method of delivering drugs to patients in such a targeted order that increases the concentration of the delivered drug only on the body part of interest (organs/tissues/cells), which in turn improves the effectiveness of the treatment while reducing side effects of drug administration. Basically, drug targeting should help the drug molecule to preferentially reach the desired site. The inherent advantage of this technique results in the administration of the required drug with its reduced dose and reduced side effect. This inherent advantage of a targeted drug delivery system is also strongly recognized by research and development in the clinical and pharmaceutical fields as the backbone of therapeutics and diagnostics. Various drug carriers that can be used in this advanced delivery system are soluble polymers, biodegradable microsphere polymers (synthetic and natural), neutrophils, fibroblasts, artificial cells, lipoproteins, liposomes, micelles, and immune micelles. The goal of a targeted drug delivery system is to prolong, localize, target, and have a protected drug interaction with the diseased.","PeriodicalId":8531,"journal":{"name":"Asian Journal of Research in Pharmaceutical Sciences","volume":"9 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Short Review on Recent Approches in Targeted Drug Dilvairy System (TDDS)\",\"authors\":\"Dhananjay D. Chaudhari, Satish D. Mali, Vaishnavi Chaudhari\",\"doi\":\"10.52711/2231-5659.2023.00008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Targeted drug delivery is an advanced method of delivering drugs to patients in such a targeted order that increases the concentration of the delivered drug only on the body part of interest (organs/tissues/cells), which in turn improves the effectiveness of the treatment while reducing side effects of drug administration. Basically, drug targeting should help the drug molecule to preferentially reach the desired site. The inherent advantage of this technique results in the administration of the required drug with its reduced dose and reduced side effect. This inherent advantage of a targeted drug delivery system is also strongly recognized by research and development in the clinical and pharmaceutical fields as the backbone of therapeutics and diagnostics. Various drug carriers that can be used in this advanced delivery system are soluble polymers, biodegradable microsphere polymers (synthetic and natural), neutrophils, fibroblasts, artificial cells, lipoproteins, liposomes, micelles, and immune micelles. The goal of a targeted drug delivery system is to prolong, localize, target, and have a protected drug interaction with the diseased.\",\"PeriodicalId\":8531,\"journal\":{\"name\":\"Asian Journal of Research in Pharmaceutical Sciences\",\"volume\":\"9 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-03-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asian Journal of Research in Pharmaceutical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52711/2231-5659.2023.00008\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Research in Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52711/2231-5659.2023.00008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

靶向给药是一种先进的给药方法,它按照靶向顺序给药,只增加给药药物在感兴趣的身体部位(器官/组织/细胞)上的浓度,从而提高治疗的有效性,同时减少给药的副作用。基本上,药物靶向应该帮助药物分子优先到达所需的位置。该技术的固有优势导致所需药物的施用,其剂量减少,副作用减少。靶向给药系统的这种固有优势也被临床和制药领域的研究和开发强烈认可为治疗学和诊断学的支柱。可用于这种先进递送系统的各种药物载体有可溶性聚合物、可生物降解的微球聚合物(合成和天然)、中性粒细胞、成纤维细胞、人造细胞、脂蛋白、脂质体、胶束和免疫胶束。靶向给药系统的目标是延长、定位、靶向并与患者产生受保护的药物相互作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Short Review on Recent Approches in Targeted Drug Dilvairy System (TDDS)
Targeted drug delivery is an advanced method of delivering drugs to patients in such a targeted order that increases the concentration of the delivered drug only on the body part of interest (organs/tissues/cells), which in turn improves the effectiveness of the treatment while reducing side effects of drug administration. Basically, drug targeting should help the drug molecule to preferentially reach the desired site. The inherent advantage of this technique results in the administration of the required drug with its reduced dose and reduced side effect. This inherent advantage of a targeted drug delivery system is also strongly recognized by research and development in the clinical and pharmaceutical fields as the backbone of therapeutics and diagnostics. Various drug carriers that can be used in this advanced delivery system are soluble polymers, biodegradable microsphere polymers (synthetic and natural), neutrophils, fibroblasts, artificial cells, lipoproteins, liposomes, micelles, and immune micelles. The goal of a targeted drug delivery system is to prolong, localize, target, and have a protected drug interaction with the diseased.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信