立体定向活检在脑肿瘤治疗中的作用:约101例

D. M
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摘要

立体定向活检(STB)的出现以及CT和MRI的发展改善了脑肿瘤的治疗。本研究的目的是评估STB在脑肿瘤治疗中的作用。材料与方法:回顾性研究2000 - 2020年在AIT IDDIR公立医院和Mustapha和Mustapha BACHA大学医院中心神经外科收集的101例连续接受STB治疗的脑肿瘤患者。病变部位深或功能(罗隆区、半球、基底节区、侧脑室、脑干和松果体区)。所有病例均在CT引导下行STB。对于松果体肿瘤,术前动脉造影和术前MRI被认为有助于避免出血性并发症。结果101例(90%)首次行STB结论性检查。STB的重复检查可以重新建立准确的诊断(5.94%),其中恶性病变(70%)。患者平均年龄46岁(3 ~ 72岁),男性居多。病变的地形分布为:75.13%位于Rolondic区、中央灰核区、脑干和松果体区;12.87%在胼胝体和侧脑室,12.5%在雄辩的浅表病变。术后并发症以死亡率(5.9%)为主,其次为部分性癫痫发作(2.98%)、严重神经系统疾病(1.98%)、双侧上睑下垂(1.98%)和偏瘫(0.99%)。围手术期死亡率从2005年前的10.45%下降到2006年后的1%(卡方;P = 0.010)。结论:在组织学不明确的情况下,应进行分期和复诊。对于MRI条件下的小的深部病变,STB是必要的。对于松果体肿瘤,必须采用经颞叶正交法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Contribution of Stereotaxic Biopsy in the Management of Brain Tumors: About 101 Cases
Introduction: The advent of Stereotaxic Biopsy (STB) and the development of CT and MRI have improved the management of brain tumours. The aim of this study is to evaluate the role of STB in the management of brain tumors. Material and Methods: Retrospective study from 2000 to 2020 concerning 101 consecutive patients with brain tumours, having benefited from a STB, collected in the neurosurgery departments of the the public hospital establishment of AIT IDDIR and Mustapha and Mustapha BACHA university hospital center. The seat of the lesion is deep or functional (the Rolondic region, hemispherical, basal ganglia, lateral ventricles and brainstem and pineal region). STB was performed under CT guidance in all cases. For pineal tumours, arteriography with venographic time and preoperative MRI has been deemed useful to avoid hemorrhagic complications. Results: In 101 cases, the STB was conclusive on the first attempt (90%). The repetition of the STB made it possible to re-establish a precise diagnosis in (5.94%) It was malignant lesions (70% of the cases). The average age of the patients was 46 years (3 to 72) with a male predominance. The topography of the lesions is: 75.13% in the Rolondic region, Central Gray Nuclei, Brainstem and pineal region; 12.87% in the corpus callosum and lateral ventricles and 12.5% in the eloquent superficial lesion. Postoperative complications are dominated by mortality 5.9% followed by partial epileptic seizure 2.98% and severe neurological disorders 1.98%, bilateral ptosis 1.98% and hemiplegia 0.99%. Perioperative mortality fell from 10.45% before 2005 to 1% after 2006 (Chi-square; p = 0.010). Conclusion: STBs should be staged and repeated in case of inconclusive histology. For small deep lesions STB under MRI conditions is necessary. For pineal tumours, it must be performed by the transtemporal orthogonal approach.
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