Proteogest:一种使用质谱法促进蛋白质组学的工具

Gerard Cagney , Andrew Emili
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引用次数: 0

摘要

在典型的蛋白质组学实验中,质谱(MS)与蛋白质或肽分离步骤相结合,用于鉴定数百到数千个肽。随着仪器和数据生成的不断进步,需要有效的软件来连接蛋白质组学分析的不同阶段。Proteogest已被开发用于对数千种蛋白质序列的生物物理特性进行描述性和统计分析,并对蛋白质组进行硅蛋白水解消化,然后进行序列分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Proteogest: a tool for facilitating proteomics using mass spectrometry

In a typical proteomic experiment, mass spectrometry (MS) is coupled to protein or peptide separation steps for the identification of many hundreds to thousands of peptides. With the continuing advances in instrumentation and data generation, effective software is needed to link the different stages of proteomic analysis. Proteogest has been developed to carry out descriptive and statistical analyses of the biophysical properties of thousands of protein sequences and to perform in silico proteolytic digestions of proteomes coupled to subsequent sequence analysis.

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