{"title":"Proteogest:一种使用质谱法促进蛋白质组学的工具","authors":"Gerard Cagney , Andrew Emili","doi":"10.1016/S1741-8372(04)02419-3","DOIUrl":null,"url":null,"abstract":"<div><p><span><span>In a typical proteomic<span> experiment, mass spectrometry (MS) is coupled to protein or peptide separation steps for the identification of many hundreds to thousands of peptides. With the continuing advances in instrumentation and data generation, effective software is needed to link the different stages of proteomic analysis. Proteogest has been developed to carry out descriptive and statistical analyses of the biophysical properties of thousands of </span></span>protein sequences and to perform </span><em>in silico</em><span> proteolytic digestions of proteomes coupled to subsequent sequence analysis.</span></p></div>","PeriodicalId":100382,"journal":{"name":"Drug Discovery Today: TARGETS","volume":"3 2","pages":"Pages 63-65"},"PeriodicalIF":0.0000,"publicationDate":"2004-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1741-8372(04)02419-3","citationCount":"0","resultStr":"{\"title\":\"Proteogest: a tool for facilitating proteomics using mass spectrometry\",\"authors\":\"Gerard Cagney , Andrew Emili\",\"doi\":\"10.1016/S1741-8372(04)02419-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span><span>In a typical proteomic<span> experiment, mass spectrometry (MS) is coupled to protein or peptide separation steps for the identification of many hundreds to thousands of peptides. With the continuing advances in instrumentation and data generation, effective software is needed to link the different stages of proteomic analysis. Proteogest has been developed to carry out descriptive and statistical analyses of the biophysical properties of thousands of </span></span>protein sequences and to perform </span><em>in silico</em><span> proteolytic digestions of proteomes coupled to subsequent sequence analysis.</span></p></div>\",\"PeriodicalId\":100382,\"journal\":{\"name\":\"Drug Discovery Today: TARGETS\",\"volume\":\"3 2\",\"pages\":\"Pages 63-65\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2004-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S1741-8372(04)02419-3\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Drug Discovery Today: TARGETS\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1741837204024193\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Drug Discovery Today: TARGETS","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1741837204024193","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Proteogest: a tool for facilitating proteomics using mass spectrometry
In a typical proteomic experiment, mass spectrometry (MS) is coupled to protein or peptide separation steps for the identification of many hundreds to thousands of peptides. With the continuing advances in instrumentation and data generation, effective software is needed to link the different stages of proteomic analysis. Proteogest has been developed to carry out descriptive and statistical analyses of the biophysical properties of thousands of protein sequences and to perform in silico proteolytic digestions of proteomes coupled to subsequent sequence analysis.