在刚果(金)圭卢省治疗镰状细胞病中应用的塞内加尔藜、堇青花和荆芥的矿物质含量和抗镰状细胞病活性

J. M. Kitadi, C. L. Inkoto, E. Lengbiye, D. Tshibangu, D. Tshilanda, K. Ngbolua, K. Taba, B. M. Mbala, B. Schmitz, P. Mpiana
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Methodology: These three plants were harvested in the province of Kwilu in Democratic Republic of the Congo. The mineral composition analysis was carried out using the fluorescence spectrometric method while the in vitro antisickling activity was evaluate using Emmel and hemolysis tests. Results: Twenty three mineral elements were identified in each of these three plants: Potassium (K), Phosphorus (P), Calcium (Ca), Sodium (Na), Magnesium (Mg), Sulphur (S), Chlorine (Cl) and trace elements as: Aluminum (Al), Silicon (Si), Vanadium (V), Chromium (Cr), Manganese (Mn), Iron (Fe), Nickel (Ni), Copper (Cu), Zinc (Zn), Selenium (Se), Brome (Br), Molybdenum (Mo), Tin (Sn), Iodine (I), Barium (Ba) and Lead (Pb). Annona senegalensis Pers., Alchornea cordifolia (Schumach. & Thonn.) Müll.Arg. and Vigna unguiculate (L.) Walp. aqueous extracts showed the capacity to prevent the sickling and the hemolysis of red blood cells. 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引用次数: 5

摘要

目的:测定几种植物的矿物成分。;;;;& Thonn)。考虑。参数。和有蹄兽(L.)Walp.)用于管理镰状细胞病的传统医生在kwulu省和评估其抗镰状细胞活性体外。Kitadi et al.;Ibrr, 11(3): 18- 27,2020;文章no.IBRR。60415 19研究设计:在Kwilu省采集植物,样品制备,抗镰状病试验和荧光光谱分析。研究地点和时间:这项工作于2016年10月至2018年1月在刚果民主共和国金沙萨大学理学院进行。方法:这三种植物是在刚果民主共和国的Kwilu省收获的。用荧光光谱法分析其矿物成分,用Emmel试验和溶血试验评价其体外抗镰刀病活性。结果:在这三种植物中分别鉴定出钾(K)、磷(P)、钙(Ca)、钠(Na)、镁(Mg)、硫(S)、氯(Cl)等23种矿物元素和微量元素:铝(Al)、硅(Si)、钒(V)、铬(Cr)、锰(Mn)、铁(Fe)、镍(Ni)、铜(Cu)、锌(Zn)、硒(Se)、溴(Br)、钼(Mo)、锡(Sn)、碘(I)、钡(Ba)和铅(Pb)。凤仙花;;;;& Thonn)。Mull.Arg。和有蹄兽(L.)Walp。水提物显示出防止红细胞镰状和溶血的能力。结论:上述结果证实了这些植物的抗镰状细胞病活性,从而证明了这些植物在传统医学中用于镰状细胞病的治疗是合理的。一些矿物元素如铁、锌、镁和硒的存在对镰状细胞病患者是有用的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mineral Content and Antisickling Activity of Annona senegalensis, Alchornea cordifolia and Vigna unguiculata Used in the Management of Sickle Cell Disease in the Kwilu Province (Congo, DR)
Aims: To determine the mineral composition of some plants (Annona senegalensis Pers., Alchornea cordifolia (Schumach. & Thonn.) Müll. Arg. and Vigna unguiculate (L.) Walp.) used in the management of sickle cell disease by traditional practitioners in Kwilu province and to evaluate their antisickling activity in vitro. Original Research Article Kitadi et al.; IBRR, 11(3): 18-27, 2020; Article no.IBRR.60415 19 Study Design: Plant collection in the Kwilu province, sample preparation, antisickling tests and fluorescence spectrometric analysis. Place and Duration of Study: This work was performed at the Faculty of Science, University of Kinshasa, Congo DR, from October 2016 to January 2018. Methodology: These three plants were harvested in the province of Kwilu in Democratic Republic of the Congo. The mineral composition analysis was carried out using the fluorescence spectrometric method while the in vitro antisickling activity was evaluate using Emmel and hemolysis tests. Results: Twenty three mineral elements were identified in each of these three plants: Potassium (K), Phosphorus (P), Calcium (Ca), Sodium (Na), Magnesium (Mg), Sulphur (S), Chlorine (Cl) and trace elements as: Aluminum (Al), Silicon (Si), Vanadium (V), Chromium (Cr), Manganese (Mn), Iron (Fe), Nickel (Ni), Copper (Cu), Zinc (Zn), Selenium (Se), Brome (Br), Molybdenum (Mo), Tin (Sn), Iodine (I), Barium (Ba) and Lead (Pb). Annona senegalensis Pers., Alchornea cordifolia (Schumach. & Thonn.) Müll.Arg. and Vigna unguiculate (L.) Walp. aqueous extracts showed the capacity to prevent the sickling and the hemolysis of red blood cells. Conclusion: The obtained results confirm the antisickling activity thus justifying the use of these plants in Traditional Medicine for the management of sickle cell disease. The presence of some mineral elements like Fe, Zn, Mg and Se are useful for sickle cell disease patients.
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