含氟氯己定与不含氟氯己定漱口水在青少年群体中的比较研究

Megha L Vyas, Ashit G. Bharwani, Dhaval Trivedi
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引用次数: 0

摘要

背景:漱口水是化学防治牙菌斑的重要手段。有强有力的证据表明,在氯己定漱口水中加入氟化物会更有效。目的:本研究计划评估含有氯己定(CHX)和胺/氟化亚锡(AmF)的漱口水与含有精油(EO)或十六烷基氯化吡啶(CPC)和氟化钠(NaF)的两种漱口水在青少年组中对斑块积聚、牙龈炎和唾液氟化物水平的影响。方法:本研究招募了90名12至20岁的健康青少年参与。实验牙龈炎模型包括2周的招募期,随后是6天的冲洗期,使用4种漱口剂中的一种进行研究。在预试期和冲洗期(第0天/第6天)结束时,记录牙龈指数(GI)、菌斑指数(PI)和唾液氟化物水平。统计学分析采用Wilcoxon符号检验和相关t检验。结果:CHX+AmF制剂冲洗液减少了牙菌斑的再生长,尽管各组之间没有显著差异(p> 0.001)。在实验期间,各配方的牙龈炎指数均显著升高(p < 0.01)。结论:对于青少年高危人群,建议在机械口腔卫生的基础上辅助使用含AmF的CHX漱口水。关键词:CT KUB,辐射安全,最小化辐射
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Comparative Study of Fluoride Containing Chlorhexidine and Non Chlorhexidine Mouthrinses in a Teenage Group
Background: Mouthwashes are important means used in chemical control of dental plaque. There is strong evidence suggestive of better effectiveness, when fluoride is added to chlorhexidine mouthwash. Objectives: The study was planned to assess the effect of a mouthrinse containing Chlorhexidine (CHX) and amine/stannous fluoride (AmF) on plaque accumulation, gingivitis and salivary fluoride levels in comparison with two mouthrinses containing either essential oils (EO) or cetylpyridinium chloride (CPC) with sodium fluoride (NaF) in a teenage group. Methodology: For this study 90 healthy teenage between 12 and 20 years were recruited for participation. The experimental gingivitis model consisted of a 2-weeks recruitment phase, followed by a 6-day rinsing period with one of the 4 mouthrinse formulations was used for the study. At the end of the pre-phase period and the rinsing period (Day-0/Day-6), gingival index (GI), plaque index (PI) and salivary fluoride levels were recorded. The statistical analyses were performed using Wilcoxon sign test and the dependent t test. Results: A reduction in plaque re-growth was seen for the CHX+AmF formulation rinse, although there were no significant differences among all groups (p>0,001). During the experimental periods, the gingivitis indices increased significantly for all formulations (p<0,001), except for the CHX+AmF formulation. The CHX+AmF formulation scored higher levels of salivary fluoride at the end of the rinsing period (p>0,001). Conclusion: We would like to conclude that the adjunctive use of AmF containing CHX mouthrinses to mechanical oral hygiene should be recommended for teenage at risk groups. Keywords: CT KUB, Radiation safety, Minimise radiation
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