Israa Burhan Raoof, Zahraa Ahmed Okhti, Mayssaa E. Abdalah
{"title":"冠状病毒-19的临床体征、实验室诊断和治疗","authors":"Israa Burhan Raoof, Zahraa Ahmed Okhti, Mayssaa E. Abdalah","doi":"10.32947/ajps.v21i1.776","DOIUrl":null,"url":null,"abstract":"Covid -19 is a viral disease play important role in danger pathogens for human, it is infecting on respiratory, hepatic, central nervous systems and gastrointestinal, in addition to that, the triggers included cytokine storm is inflammatory response to viral infection \n \n \nTherefore, excessive enhance of immune cells lead to new of pro-inflammatory cytokines. COVID-19 interaction with the cardiovascular system on different levels, rising death percent in people underlying cardiovascular state provoking myocardial injury. Respiratory infection varying from mild cold to the severe illness like as Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome the most important coronavirus (COVID-19) complications, however individuals with asymptomatic disease were also suspected of possible infectious transmission, which further adds to the uncertainty of the dynamic of disease transmission in COVID-19 infections, Suppression of angiotensin-converting enzyme (ACE2) expression by inflammatory cytokines accompanied by the decrease of estrogens and androgens of the elderly, establish a negative correlation between ACE2 expression and mortality in other cases may lead to infertility. Early detection by PCR has aided the identification of the pathogen at an early level. Furthermore, the treatment includes the effectiveness of glucocorticoid drugs (dexamethasone), anti-malaria drug (hydroxychloroquine), azithromycin (antibacterial drug) and favipiravir are all drugs recommended in illness with Covid-19. Remdesivir suppression COVID-19 replication and decreases viral load, alleviates clinical signs and improves pulmonary injury, therefore Remdesivir drug has been used as a compassionate medicine for treating COVID-19 patients.","PeriodicalId":7406,"journal":{"name":"Al Mustansiriyah Journal of Pharmaceutical Sciences","volume":"40 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Clinical Signs, Laboratory Diagnosis and Treatments Involved in Corona Viruses-19\",\"authors\":\"Israa Burhan Raoof, Zahraa Ahmed Okhti, Mayssaa E. Abdalah\",\"doi\":\"10.32947/ajps.v21i1.776\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Covid -19 is a viral disease play important role in danger pathogens for human, it is infecting on respiratory, hepatic, central nervous systems and gastrointestinal, in addition to that, the triggers included cytokine storm is inflammatory response to viral infection \\n \\n \\nTherefore, excessive enhance of immune cells lead to new of pro-inflammatory cytokines. COVID-19 interaction with the cardiovascular system on different levels, rising death percent in people underlying cardiovascular state provoking myocardial injury. Respiratory infection varying from mild cold to the severe illness like as Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome the most important coronavirus (COVID-19) complications, however individuals with asymptomatic disease were also suspected of possible infectious transmission, which further adds to the uncertainty of the dynamic of disease transmission in COVID-19 infections, Suppression of angiotensin-converting enzyme (ACE2) expression by inflammatory cytokines accompanied by the decrease of estrogens and androgens of the elderly, establish a negative correlation between ACE2 expression and mortality in other cases may lead to infertility. Early detection by PCR has aided the identification of the pathogen at an early level. Furthermore, the treatment includes the effectiveness of glucocorticoid drugs (dexamethasone), anti-malaria drug (hydroxychloroquine), azithromycin (antibacterial drug) and favipiravir are all drugs recommended in illness with Covid-19. Remdesivir suppression COVID-19 replication and decreases viral load, alleviates clinical signs and improves pulmonary injury, therefore Remdesivir drug has been used as a compassionate medicine for treating COVID-19 patients.\",\"PeriodicalId\":7406,\"journal\":{\"name\":\"Al Mustansiriyah Journal of Pharmaceutical Sciences\",\"volume\":\"40 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-04-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Al Mustansiriyah Journal of Pharmaceutical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32947/ajps.v21i1.776\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Al Mustansiriyah Journal of Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32947/ajps.v21i1.776","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Clinical Signs, Laboratory Diagnosis and Treatments Involved in Corona Viruses-19
Covid -19 is a viral disease play important role in danger pathogens for human, it is infecting on respiratory, hepatic, central nervous systems and gastrointestinal, in addition to that, the triggers included cytokine storm is inflammatory response to viral infection
Therefore, excessive enhance of immune cells lead to new of pro-inflammatory cytokines. COVID-19 interaction with the cardiovascular system on different levels, rising death percent in people underlying cardiovascular state provoking myocardial injury. Respiratory infection varying from mild cold to the severe illness like as Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome the most important coronavirus (COVID-19) complications, however individuals with asymptomatic disease were also suspected of possible infectious transmission, which further adds to the uncertainty of the dynamic of disease transmission in COVID-19 infections, Suppression of angiotensin-converting enzyme (ACE2) expression by inflammatory cytokines accompanied by the decrease of estrogens and androgens of the elderly, establish a negative correlation between ACE2 expression and mortality in other cases may lead to infertility. Early detection by PCR has aided the identification of the pathogen at an early level. Furthermore, the treatment includes the effectiveness of glucocorticoid drugs (dexamethasone), anti-malaria drug (hydroxychloroquine), azithromycin (antibacterial drug) and favipiravir are all drugs recommended in illness with Covid-19. Remdesivir suppression COVID-19 replication and decreases viral load, alleviates clinical signs and improves pulmonary injury, therefore Remdesivir drug has been used as a compassionate medicine for treating COVID-19 patients.