帕金森病:有什么新发现?

S. Khadilkar, H. Oza, Hiral Halani, J. Lalkaka
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引用次数: 2

摘要

运动和非运动临床特征见表1。目前的文献表明帕金森病患者的临床发展有三个不同的阶段,如表2所示,重视前两个阶段是很重要的。最近增加了一个新的亚类别“临床遗传学PD”。帕金森病(PD)是全球老年人群中最常见的运动障碍之一。它是一种复杂的进行性神经退行性疾病,具有异质性运动和非运动临床特征。近年来的研究进展在该病的病理生理、诊断和治疗方面取得了显著进展。我们希望强调这些最近的发展有可能在不久的将来改变PD在常规临床实践中的管理。本文将讨论当前的发展,在诊断,病理生理学,特别是治疗方面,这种常见病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Parkinson’s Disease: What is New?
motor and non-motor clinical features are Table 1. Literature now suggests three different stages in clinical evolution of a patient with PD as depicted Table 2 and it is important to appreciate the first two stages. A new subcategory of ‘clinico-genetic PD’ has been added recently. ABSTRACT Parkinson disease (PD) is one of the most common movement disorders in elderly population worldwide. It is a complex, progressive neurodegenerative disease with a constellation of heterogeneous motor and non-motor clinical features. Research developments in recent years have made remarkable progress in pathophysiology, diagnosis, and treatment of this disease. We wish to highlight these recent developments that have the potential to change the management of PD in routine clinical practice in near future. This manuscript will discuss the current developments in the diagnosis, pathophysiology and particularly, the treatment aspects of this commonly encountered disease.
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