吸烟对年轻吸烟者血液动力学参数和血脂的影响

BHUPENDRA KUMAR JAIN, Ashwin Songara, U. Chandrakantham, J. Nagwanshi
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引用次数: 0

摘要

背景和目的:烟草使用与心血管、呼吸和周围血管疾病有关。随着吸烟量的增加,吸烟对年轻吸烟者的血液动力学参数和血脂的短期影响仍有争议。本研究的目的是评估吸烟对年轻吸烟者重要血液动力学参数和血脂的影响。材料和方法:本研究是在一家三级医院进行的一项为期18个月的观察性横断面研究,研究对象包括吸烟者和非吸烟者。采集血压、心率、血氧饱和度(SPO2)、血脂等重要血液动力学参数。采用卡方检验和方差分析(ANOVA)检验对数据进行分析。结果:共有80名吸烟者和80名非吸烟者参加了这项研究。与吸烟者相比,不吸烟者的血压、心率和平均SpO2显著(p<0.001)降低。非吸烟者的屏气时间(BHT)和单次呼吸计数(SBC)更高。吸烟者的总胆固醇(T-chol)、低密度脂蛋白(LDL)和甘油三酯(TG)均值显著高于非吸烟者(p<0.001),而高密度脂蛋白(HDL)均值显著低于非吸烟者。随着吸烟量的增加,收缩压、T -chol、TG显著升高(p<0.05)。结论:吸烟与各年龄段重要血流动力学参数和血脂紊乱有关。应该组织反吸烟运动,既不鼓励个人吸烟,也不鼓励在公共场所吸烟。中华医学会医学杂志。2023。17(1): 007。DOI: https://doi.org/10.55010/imcjms.17.007*Correspondence: Bhupendra Kumar Jain,印度中央邦恰德瓦拉贾巴尔普尔医科大学恰德瓦拉医学院肺医学系。电子邮件:drbhupendrakjain@gmail.com
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of smoking on vital hemodynamic parameters and lipid profile of young smokers
Background and objectives: Tobacco use is associated with cardiovascular, respiratory and peripheral vascular diseases. The short term effects of tobacco smoking on vital hemodynamic parameters and lipid profile of young smoker with increased quantity of smoking is still debatable. The objective of this study was to evaluate the effect of smoking on vital hemodynamic parameters and lipid profile of young smokers. Materials and methods: The current study was an observational cross sectional study conducted in a tertiary care hospital over a period of 18 months and included smokers and non-smokers. Data on vital hemodynamic parameters like blood pressure, heart rate, oxygen saturation (SPO2) and lipid profile were collected. Chi-square and analysis of variance (ANOVA) tests were used to analyze the data. Results: A total of 80 smokers and 80 non-smokers were enrolled in the study. Blood pressure, heart rate and mean SpO2 were significantly (p<0.001) lower in non-smokers compared to smokers. Breath holding time (BHT) and single breath count (SBC) were higher in non-smokers. Mean values of total cholesterol (T-chol), low density lipoprotein (LDL) and triglyceride (TG) were significantly (p<0.001) higher in smokers than non-smokers, while high density lipoprotein (HDL) was significantly low in smokers. SBP, T -chol and TG significantly (p<0.05) increased as the quantity of smoking increased. Conclusion: Smoking is associated with derangement of vital hemodynamic parameters and lipid profile across the age. Anti-smoking campaign should be organized to discourage both personal smoking and smoking in public places. IMC J Med Sci. 2023. 17(1): 007. DOI : https://doi.org/10.55010/imcjms.17.007 *Correspondence: Bhupendra Kumar Jain, Department of Pulmonary Medicine, School of Chhindwara Institute Of Medical Sciences, Jabalpur Medical University, Chhindwara, Madhya Pradesh, India. Email: drbhupendrakjain@gmail.com
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