The Beneficial Effects of Different Types of Olive Oil, Flaxseed Oil and Their Blend on CCl4 – Induced Liver Hepatitis in Rats

In recent years, liver diseases became one of the very important worldwide health problems (Kavitha et al. 2011). Liver was found to be subjected to recurrent metabolic insults because of it is accomplish an indispensable assignment in detoxification, metabolism of a variety of drugs and xenobiotics and exposure to toxic chemicals including insecticides, pesticides and environmental pollutants (Sethuraman, 2003). CCl 4 was reported to be used in animal models to study the chemical toxin-induced liver damage (Elbakry et al., 2017). The toxicity of CCl 4 is attributed to its metabolized and producing a highly reactive free radicals and oxygen species which lead to lipid peroxidation of cell lipid and liver injury (Manickam et al., 2017). The hepatocyte injury of liver including that relating to CCl 4 was found to activate the Kupffer cells which promote tissue damage (Muriel and Escobar, 2003).