Régulo López-Callejas , Rosendo Peña-Eguiluz , Raúl Valencia-Alvarado , Antonio Mercado-Cabrera , Benjamín G. Rodríguez-Méndez , Jorge H. Serment-Guerrero , Agustín Cabral-Prieto , A. Concepción González-Garduño , N. Alberto Domínguez-Cadena , Jorge Muñoz-Infante , Mario Betancourt-Ángeles
{"title":"血浆针治疗糖尿病足的替代方法","authors":"Régulo López-Callejas , Rosendo Peña-Eguiluz , Raúl Valencia-Alvarado , Antonio Mercado-Cabrera , Benjamín G. Rodríguez-Méndez , Jorge H. Serment-Guerrero , Agustín Cabral-Prieto , A. Concepción González-Garduño , N. Alberto Domínguez-Cadena , Jorge Muñoz-Infante , Mario Betancourt-Ángeles","doi":"10.1016/j.cpme.2018.01.001","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><p>This case report deals with helium cold plasma as an alternative therapy for healing diabetic foot infections.</p></div><div><h3>Methods</h3><p><span>A surgical cleaning of neuropathic ulceration was performed before each one of three diary 0.025 Ls</span><sup>−1</sup><span> helium plasma needle treatments with a duration in time of 180 s over the entire wound area. The distance between the output reactor and the wound surface varied between 3 and 5 mm, meanwhile the plasma dose was keept at 0.42 W/cm</span><sup>2</sup>.</p></div><div><h3>Results</h3><p>An 83-year-old female patient with diabetes mellitus type 2, diagnosed 25 years ago, presented with a chronic ulcer on the left foot was treated with cold plasma. It was applied as circular movements of approximately 10 mm displacement, covering an area of around 10 mm<sup>2</sup> and continuing this procedure until completely covering the wound, trying to provide a uniform treatment over the entire surface of the wound.</p></div><div><h3>Conclusion</h3><p><span><span>The wound presented ischemia, and according to the classification DEPA had a score of 10, which implied a poor healing prognosis and even had the risk of amputation of the foot. After application of the plasma-based treatment the healing of the chronic wound was promoted due a higher proliferation of </span>endothelial cells that are the promoters of </span>angiogenesis.</p></div>","PeriodicalId":46325,"journal":{"name":"Clinical Plasma Medicine","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cpme.2018.01.001","citationCount":"13","resultStr":"{\"title\":\"Alternative method for healing the diabetic foot by means of a plasma needle\",\"authors\":\"Régulo López-Callejas , Rosendo Peña-Eguiluz , Raúl Valencia-Alvarado , Antonio Mercado-Cabrera , Benjamín G. Rodríguez-Méndez , Jorge H. Serment-Guerrero , Agustín Cabral-Prieto , A. Concepción González-Garduño , N. Alberto Domínguez-Cadena , Jorge Muñoz-Infante , Mario Betancourt-Ángeles\",\"doi\":\"10.1016/j.cpme.2018.01.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Purpose</h3><p>This case report deals with helium cold plasma as an alternative therapy for healing diabetic foot infections.</p></div><div><h3>Methods</h3><p><span>A surgical cleaning of neuropathic ulceration was performed before each one of three diary 0.025 Ls</span><sup>−1</sup><span> helium plasma needle treatments with a duration in time of 180 s over the entire wound area. The distance between the output reactor and the wound surface varied between 3 and 5 mm, meanwhile the plasma dose was keept at 0.42 W/cm</span><sup>2</sup>.</p></div><div><h3>Results</h3><p>An 83-year-old female patient with diabetes mellitus type 2, diagnosed 25 years ago, presented with a chronic ulcer on the left foot was treated with cold plasma. It was applied as circular movements of approximately 10 mm displacement, covering an area of around 10 mm<sup>2</sup> and continuing this procedure until completely covering the wound, trying to provide a uniform treatment over the entire surface of the wound.</p></div><div><h3>Conclusion</h3><p><span><span>The wound presented ischemia, and according to the classification DEPA had a score of 10, which implied a poor healing prognosis and even had the risk of amputation of the foot. After application of the plasma-based treatment the healing of the chronic wound was promoted due a higher proliferation of </span>endothelial cells that are the promoters of </span>angiogenesis.</p></div>\",\"PeriodicalId\":46325,\"journal\":{\"name\":\"Clinical Plasma Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.cpme.2018.01.001\",\"citationCount\":\"13\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Plasma Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2212816617300161\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Plasma Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212816617300161","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
Alternative method for healing the diabetic foot by means of a plasma needle
Purpose
This case report deals with helium cold plasma as an alternative therapy for healing diabetic foot infections.
Methods
A surgical cleaning of neuropathic ulceration was performed before each one of three diary 0.025 Ls−1 helium plasma needle treatments with a duration in time of 180 s over the entire wound area. The distance between the output reactor and the wound surface varied between 3 and 5 mm, meanwhile the plasma dose was keept at 0.42 W/cm2.
Results
An 83-year-old female patient with diabetes mellitus type 2, diagnosed 25 years ago, presented with a chronic ulcer on the left foot was treated with cold plasma. It was applied as circular movements of approximately 10 mm displacement, covering an area of around 10 mm2 and continuing this procedure until completely covering the wound, trying to provide a uniform treatment over the entire surface of the wound.
Conclusion
The wound presented ischemia, and according to the classification DEPA had a score of 10, which implied a poor healing prognosis and even had the risk of amputation of the foot. After application of the plasma-based treatment the healing of the chronic wound was promoted due a higher proliferation of endothelial cells that are the promoters of angiogenesis.
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