Okwute Michael Ochayi, B. Anyaehie, E. Iyare, Danazumi Umar Haruna, Andrew E. Ivang
{"title":"酵母硒对噪声应激孕鼠认知能力的影响","authors":"Okwute Michael Ochayi, B. Anyaehie, E. Iyare, Danazumi Umar Haruna, Andrew E. Ivang","doi":"10.9734/arrb/2022/v37i130479","DOIUrl":null,"url":null,"abstract":"A total of twelve pregnant Wistar rats were used, and randomly divided into three groups (n=4). Group A (negative control), not exposed to noise stress), group B (1mL/kg of distilled water + 4h /15 days noise stress), group C (0.04 mg/kg) of selenium-yeast + 4 h/15 days noise stress). On day 18 and 19 of gestation cognitive tests were conducted using Y-maze and Novel Object Recognition Test. A significant increase (P ˂ 0.05) was observed in the percentage alternation and discrimination index in group A compared with group B. However, the percentage alternation and DI were significantly (P ˂ 0.05) decreased in group C compared with group B. In conclusion, noise stress induces cognitive deficit, this deficit can be mitigated with the administration of selenium-yeast.","PeriodicalId":8230,"journal":{"name":"Annual research & review in biology","volume":"83 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Effect of Selenium-yeast on Cognitive Performance on Pregnant Dams Exposed to Noise Stress\",\"authors\":\"Okwute Michael Ochayi, B. Anyaehie, E. Iyare, Danazumi Umar Haruna, Andrew E. Ivang\",\"doi\":\"10.9734/arrb/2022/v37i130479\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A total of twelve pregnant Wistar rats were used, and randomly divided into three groups (n=4). Group A (negative control), not exposed to noise stress), group B (1mL/kg of distilled water + 4h /15 days noise stress), group C (0.04 mg/kg) of selenium-yeast + 4 h/15 days noise stress). On day 18 and 19 of gestation cognitive tests were conducted using Y-maze and Novel Object Recognition Test. A significant increase (P ˂ 0.05) was observed in the percentage alternation and discrimination index in group A compared with group B. However, the percentage alternation and DI were significantly (P ˂ 0.05) decreased in group C compared with group B. In conclusion, noise stress induces cognitive deficit, this deficit can be mitigated with the administration of selenium-yeast.\",\"PeriodicalId\":8230,\"journal\":{\"name\":\"Annual research & review in biology\",\"volume\":\"83 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-01-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annual research & review in biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.9734/arrb/2022/v37i130479\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annual research & review in biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.9734/arrb/2022/v37i130479","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effect of Selenium-yeast on Cognitive Performance on Pregnant Dams Exposed to Noise Stress
A total of twelve pregnant Wistar rats were used, and randomly divided into three groups (n=4). Group A (negative control), not exposed to noise stress), group B (1mL/kg of distilled water + 4h /15 days noise stress), group C (0.04 mg/kg) of selenium-yeast + 4 h/15 days noise stress). On day 18 and 19 of gestation cognitive tests were conducted using Y-maze and Novel Object Recognition Test. A significant increase (P ˂ 0.05) was observed in the percentage alternation and discrimination index in group A compared with group B. However, the percentage alternation and DI were significantly (P ˂ 0.05) decreased in group C compared with group B. In conclusion, noise stress induces cognitive deficit, this deficit can be mitigated with the administration of selenium-yeast.
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