J. Chand, S. Sultana, G. Sekhar, D. Tony, N. R. Lakshmi, A. N. Babu, R. Nadendla
{"title":"白参改善阿尔茨海默病模型大鼠记忆和学习的实验研究","authors":"J. Chand, S. Sultana, G. Sekhar, D. Tony, N. R. Lakshmi, A. N. Babu, R. Nadendla","doi":"10.20902/IJPTR.2019.120101","DOIUrl":null,"url":null,"abstract":"Alzheimer’s disease (AD) affects the central nervous system causing progressive degeneration of neurons, which affect cognitive function of the individual. So, the aim of this study was to identify the potential of aqueous and methanolic stem extracts of Securinega leucopyrus to be used as a therapeutic agent against Alzheimer’s disease. The cognitive impairment was produced by the methods, ethanolinduced cognitive impairment &diazepam induced amnesia. The potentials of the extracts were determined by using Morris water maze (MWM) test. Both the extracts showed significant learning and memory enhancement activity.","PeriodicalId":14252,"journal":{"name":"International Journal of PharmTech Research","volume":"5 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Securinega leucopyrus improves Memory and Learning in Alzheimer’s Model: An Experimental Study in Rat\",\"authors\":\"J. Chand, S. Sultana, G. Sekhar, D. Tony, N. R. Lakshmi, A. N. Babu, R. Nadendla\",\"doi\":\"10.20902/IJPTR.2019.120101\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Alzheimer’s disease (AD) affects the central nervous system causing progressive degeneration of neurons, which affect cognitive function of the individual. So, the aim of this study was to identify the potential of aqueous and methanolic stem extracts of Securinega leucopyrus to be used as a therapeutic agent against Alzheimer’s disease. The cognitive impairment was produced by the methods, ethanolinduced cognitive impairment &diazepam induced amnesia. The potentials of the extracts were determined by using Morris water maze (MWM) test. Both the extracts showed significant learning and memory enhancement activity.\",\"PeriodicalId\":14252,\"journal\":{\"name\":\"International Journal of PharmTech Research\",\"volume\":\"5 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of PharmTech Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.20902/IJPTR.2019.120101\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of PharmTech Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20902/IJPTR.2019.120101","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Securinega leucopyrus improves Memory and Learning in Alzheimer’s Model: An Experimental Study in Rat
Alzheimer’s disease (AD) affects the central nervous system causing progressive degeneration of neurons, which affect cognitive function of the individual. So, the aim of this study was to identify the potential of aqueous and methanolic stem extracts of Securinega leucopyrus to be used as a therapeutic agent against Alzheimer’s disease. The cognitive impairment was produced by the methods, ethanolinduced cognitive impairment &diazepam induced amnesia. The potentials of the extracts were determined by using Morris water maze (MWM) test. Both the extracts showed significant learning and memory enhancement activity.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
