低强度(0.2T)静磁场对人胶质母细胞瘤细胞核固结环的分散作用

S. C. Kim, W. Im, Beom Jin Kim
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引用次数: 0

摘要

生物磁学是细胞系操纵的重要生物技术领域之一。然而,其在细胞周围水平的调控,在刺激后还不完全发达。胶质母细胞瘤U87和U251是快速生长肿瘤的恶性模型。利用静磁场的快速增长特性,研究了静磁场(0.2T=2000±600高斯)在细胞水平上的色散。结果,细胞骨架蛋白核锚蛋白G分散。透射电镜下的膜屏障显示膜器官的改变。我们的研究结果带来了一个见解,即静态磁刺激产生了一个特定的细胞质胞内模式
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Low Intensity (0.2T) Static Magnetic Field for Dispersing Nucleus AnkyrinG in Human Cultured Glioblastoma Cells
Biomagnetism is one of important biotechnology fields for manipulation of cell lines. However, its peri-cellular level regulation, upon stimulation is not fully developed. Glioblastoma U87 and U251 represent a malignant model in rapid growing cancer. We focused in cellular level dispersion of static magnetic fields (0.2T=2000 ± 600 Gauss), using its fast growing properties. As a result, cytoskeletal protein nuclear Ankyrin G was dispersed. Membrane barriers in TEM microscopy indicated the membranous apparatus change. Our findings bring an insight that static magnetic stimulation creates a specified cytoplasmic intracellular pattern
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