Kolfinna Gautadottir, I. Gudmundsdottir, M. Sigurdsson, K. Andersen
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引用次数: 2
摘要
近年来,急性心肌梗死(AMI)的发病率在年轻人中可能没有像在普通人群中下降那么多。本研究的目的是探讨冰岛年轻AMI患者的发病率、危险因素及预后。材料与方法本研究为回顾性病例对照研究。数据来自SCAAR-SWEDEHEART数据库、Landspitali大学医院的医疗记录和卫生部的死亡登记册。比较2014-2020年冰岛诊断为AMI (STEMI/NSTEMI)的女性≤55岁、男性≤50岁患者与老年患者的流行病学。结果2852例患者中,年轻344例(占12%)。在研究期间,年轻患者的AMI发生率未见变化。STEMI在年轻患者中的比例更高(52%对35%,p30 kg/m2)(47%对36%,p<0.01),年轻患者比老年患者更普遍。老年患者更有可能在AMI发生后的一年内死亡,包括全因死亡(7%对3%,p<0.05)和心血管死亡(7%对3%,p<0.05)。没有发现年轻和老年患者AMI复发率的差异(2% vs 3%, p=0.3)。结论在研究期间,未发现年轻患者AMI发病率的变化。年轻AMI患者的危险因素与老年AMI患者不同,其死亡率较低,但AMI复发的风险相同。
[Acute myocardial infarction in young adults: incidence, risk factors and prognosis].
INTRODUCTION
The incidence of acute myocardial infarction (AMI) might not be decreasing as much among young adults as in the general population in recent years. The goal of our study was to explore incidence, risk factors and prognosis of AMI among young patients in Iceland.
MATERIAL AND METHODS
This was a retrospective case control study. The data was obtained from the SCAAR-SWEDEHEART database, medical records from Landspitali University Hospital and the death register from the Directorate of Health. The epidemiology of women ≤55 years and men ≤50 years diagnosed with AMI (STEMI/NSTEMI) in Iceland in 2014-2020 was compared with older patients.
RESULTS
Of all the cases (2852), 344 patients (12%) were young. No change was demonstrated in the incidence of AMI in the young patients during the study period. The proportion of STEMI was higher among young patients (52% vs. 35%, p<0.001). Smoking (50% vs. 26%, p<0.001) and obesity (BMI>30 kg/m2)(47% vs. 36%, p<0.01) were more prevalent in younger patiens compared to the older. Older patients were more likely to die in the year following the AMI, both from all-cause (7% vs. 3%, p<0.05) and cardiovascular mortality (7% vs. 3%, p<0.05). A difference in recurrent AMI between the young and older patients was not demonstrated (2% vs. 3%, p=0.3).
CONCLUSION
During the research period, a change in the incidence of AMI among young patients, was not demonstrated. Younger patients with AMI have different risk factors than older patients, they have lower mortality rate but the same risk of recurrent AMI.
期刊介绍:
Læknablaðið er fræðirit sem birtir vísinda og yfirlitsgreinar og annað efni sem byggir á rannsóknum innan læknisfræði eða skyldra greina. Læknablaðið er gefið út af Læknafélagi Íslands. Blaðið er sent til allra félagsmanna. Það var fyrst gefið út árið 1904 en hefur komið samfellt út frá árinu 1915. Blaðið kemur út 11 sinnum á ári og er prentað í 2000 eintökum. Allt efni Læknablaðsins frá árinu 2000 er aðgengilegt á heimasíðu blaðsins á laeknabladid.is og er aðgangur endurgjaldslaus og öllum opinn.