藤花和叶提取物的绿色合成:表征及其对结直肠癌细胞系的抗增殖活性

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引用次数: 0

摘要

自古以来,许多植物物种就被用来治疗严重的疾病。在各种药用植物中已经观察到广泛的多样化,这些植物确实能够治疗几种致命的疾病。次级代谢物的存在是其药用特性的高度优先考虑。本研究以黄钟属灌木(T. stans)为研究对象,黄钟属灌木广泛生长在热带和亚热带地区。虽然对这种植物的药用价值进行了许多研究,但对癌症治疗和纳米医学的研究却不多。绿色合成银纳米颗粒是一种环保的方法,可以将药物输送到目标尺寸。纳米外观是这些化合物的附加优势。因此,它正在医学中出现。结直肠癌是全球第四大致命疾病。因此,紫花苜蓿花和叶提取物合成的银纳米颗粒对结直肠癌细胞系(HCT 116和SW 480)具有细胞毒性和伤口愈合特性。采用紫外可见分光光度法和粒度分析仪对银纳米粒子的合成进行了验证。这些结果表明,银纳米颗粒合成的植物提取物具有良好的药理作用,有望作为一种新型药物应用于化疗领域。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Green Synthesis of Tecoma stans Flower and Leaf Extracts: Characterization and Anti-Proliferative Activity in Colorectal Cancer Cell Lines
Since times immemorial, many plant species have been utilized to cure severe diseases. A wide range of diversification has been observed in various medicinal plants, which are indeed able to cure several deadly diseases. The presence of secondary metabolites is a high priority for their medicinal characteristics. This study focused on T. stans (Yellow bells), a shrub that grows profoundly in tropical and sub-tropical regions. Although many studies have been done on the medicinal value of this plant, not much has been done on cancer treatment and nanomedicine. Green synthesized silver nanoparticles are an eco-friendly approach to delivering the drug to the target size. Nano appearance is an add-on advantage of these compounds. Hence, it is emerging in medicine. Colorectal cancer is the fourth deadliest one globally. Hence the synthesized silver nanoparticles of T. stans flower and leaf extracts showed cytotoxically and wound healing properties on colorectal cancer cell lines (HCT 116 and SW 480). Synthesis of silver nanoparticles confirmation is done by Ultra Violet Visible spectrophotometry and Particle size analyzer. All the results showcase the beneficial effects of silver nanoparticles synthesized plant extracts and may be used as a novel medicine in the field of chemotherapy.
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