{"title":"胚胎植入前遗传学诊断。","authors":"A. Safran, N. Laufer","doi":"10.1159/000082225","DOIUrl":null,"url":null,"abstract":"Preimplantation genetic diagnosis (PGD) involves testing for specific genetic conditions prior to the implantation [5] of an embryo in the uterine wall. This form of genetic screening has been made possible by the growth of in-vitro fertilization [6] (IVF) technology, which allows for the early stages of development to occur in a laboratory dish rather than in vivo [7]. The purpose of PGD is to identify what are considered to be abnormal embryos in order to select the most desirable embryos for implantation [5]. Diagnosis is comprised of two steps: extraction of one or two cells from an IVF-produced embryo, and application of the PGD test. PGD is important to embryology [8] because it has advanced IVF results and allowed couples more opportunities to deliver a child to term; however, it has also created much controversy.","PeriodicalId":7016,"journal":{"name":"Acta Europaea fertilitatis","volume":"10 1","pages":"166-201"},"PeriodicalIF":0.0000,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Preimplantation genetic diagnosis.\",\"authors\":\"A. Safran, N. Laufer\",\"doi\":\"10.1159/000082225\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Preimplantation genetic diagnosis (PGD) involves testing for specific genetic conditions prior to the implantation [5] of an embryo in the uterine wall. This form of genetic screening has been made possible by the growth of in-vitro fertilization [6] (IVF) technology, which allows for the early stages of development to occur in a laboratory dish rather than in vivo [7]. The purpose of PGD is to identify what are considered to be abnormal embryos in order to select the most desirable embryos for implantation [5]. Diagnosis is comprised of two steps: extraction of one or two cells from an IVF-produced embryo, and application of the PGD test. PGD is important to embryology [8] because it has advanced IVF results and allowed couples more opportunities to deliver a child to term; however, it has also created much controversy.\",\"PeriodicalId\":7016,\"journal\":{\"name\":\"Acta Europaea fertilitatis\",\"volume\":\"10 1\",\"pages\":\"166-201\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2005-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Europaea fertilitatis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000082225\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Europaea fertilitatis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000082225","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Preimplantation genetic diagnosis (PGD) involves testing for specific genetic conditions prior to the implantation [5] of an embryo in the uterine wall. This form of genetic screening has been made possible by the growth of in-vitro fertilization [6] (IVF) technology, which allows for the early stages of development to occur in a laboratory dish rather than in vivo [7]. The purpose of PGD is to identify what are considered to be abnormal embryos in order to select the most desirable embryos for implantation [5]. Diagnosis is comprised of two steps: extraction of one or two cells from an IVF-produced embryo, and application of the PGD test. PGD is important to embryology [8] because it has advanced IVF results and allowed couples more opportunities to deliver a child to term; however, it has also created much controversy.